Bourdon R
Laboratoire de Chimie Analytique, UER de Sciences Pharmaceutiques, Paris.
Ann Pharm Fr. 1991;49(2):67-75.
Toxicomania and doping give rise to an increasing number of drug measurements in the body fluids. Consequently the analysts have to face, at one and the same time, ethical and analytical problems. Should the analyst participate to investigations organised in order to disclose a toxicomania in a working place? The author suggests a positive answer as long as the adduct person benefits to a social and medical care. What is the analytical meaning of a positive test? Taking into account the increasing sensitivity of the methods used, thresholds have to be established, at least for the blood concentrations of the licit drugs, in order to avoid asserving the legality to the sensitivity of the apparatus.
药物成瘾和兴奋剂使用导致越来越多的体液药物检测。因此,分析人员不得不同时面对伦理和分析问题。分析人员是否应该参与为揭露工作场所药物成瘾而组织的调查?作者建议只要被检测者能得到社会和医疗护理,就给出肯定答案。阳性检测结果的分析意义是什么?考虑到所用方法的灵敏度不断提高,必须设定阈值,至少对于合法药物的血药浓度要设定阈值,以避免将合法性与仪器的灵敏度挂钩。