Traynor A E, Gertz M A, Kyle R A
Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN 55905.
Ann Neurol. 1991 Apr;29(4):451-4. doi: 10.1002/ana.410290421.
We report 6 patients for whom cranial neuropathy was a major manifestation of primary amyloidosis. In 3 of the 6, multiple cranial nerves were involved. All had tissue biopsy documentation of amyloidosis. In 2, nerve biopsy also confirmed amyloidosis. All had renal involvement manifested by proteinuria. Primary systemic amyloidosis must be considered in the differential diagnosis of cranial neuropathy, especially when proteinuria is present.
我们报告了6例以颅神经病变为原发性淀粉样变性主要表现的患者。6例中有3例累及多条颅神经。所有患者均有淀粉样变性的组织活检记录。其中2例神经活检也证实为淀粉样变性。所有患者均有蛋白尿表现的肾脏受累情况。在颅神经病变的鉴别诊断中必须考虑原发性系统性淀粉样变性，尤其是存在蛋白尿时。
