Chalidis Byron E, Dimitriou Christos G
Department of Orthopedic Surgery, University of California-San Francisco, 500 Parnassus Avenue, San Francisco, CA 94143-2203, USA.
Orthopedics. 2008 Jun;31(6):608.
Giant cell tumors of the distal radius have been frequently described as difficult to treat, chiefly because of their close proximity to multiple tendons, median nerve, radial artery and carpus.The aim of treatment is to remove the tumor completely and preserve the radiocarpal and radioulnar joints.However, this is not always feasible as giant cell tumors seem to behave more aggressively and have a higher recurrence rate in the distal radius, even if local adjuvant treatment with phenolmethylmethacrylate or liquid nitrogen is applied. The above incidence is increased in Campanacci grade III lesions, which are characterized by fuzzy borders, loss of cortical continuity, and extension into soft tissues. In these cases, wide excision instead of intralesional excision may be advocated, particularly when the tumor breaks through the cortex, violates the articular surface, and destroys >50% of the surrounding metaphysis. Several reconstructive options (e.g., resection arthroplasty, prosthetic replacement, arthrodesis, ulnar translocation, centralization of the carpus over the remaining ulna, use of a nonvascularized, or vascularized fibular graft [with or without arthrodesis], and allograft replacement) have been described for the treatment of either recurrent or primary grade III giant cell tumor with destruction of the bone cortex and associated soft tissue mass. Ulnar translocation has been mentioned rarely in the literature, and, according to our knowledge, only 10 cases have been previously reported. This article presents a case of a woman with a grade III giant cell tumor of the distal radius. Wide excision of the tumor followed by reconstruction of the distal forearm with a modified ulnar translocation technique and wrist arthrodesis led to optimum results and no mass recurrence at 13 years postoperatively.
桡骨远端骨巨细胞瘤常被描述为难以治疗,主要原因是其紧邻多条肌腱、正中神经、桡动脉和腕关节。治疗目的是彻底切除肿瘤并保留桡腕关节和桡尺关节。然而,这并不总是可行的,因为骨巨细胞瘤在桡骨远端似乎侵袭性更强且复发率更高,即便应用了甲基丙烯酸苯酚酯或液氮进行局部辅助治疗。上述情况在坎帕纳奇III级病变中更为常见,其特征为边界模糊、皮质连续性丧失以及向软组织浸润。在这些病例中,可能主张行广泛切除而非病灶内切除,尤其是当肿瘤突破皮质、侵犯关节面且破坏周围干骺端超过50%时。对于复发性或原发性III级骨巨细胞瘤伴骨皮质破坏及相关软组织肿块的治疗,已有多种重建选择(如切除关节成形术、假体置换、关节融合术、尺骨移位、腕骨在剩余尺骨上的中心化、使用非血管化或血管化腓骨移植[伴或不伴关节融合术]以及同种异体骨置换)被描述。尺骨移位在文献中很少被提及,据我们所知,此前仅报道过10例。本文介绍了1例患有桡骨远端III级骨巨细胞瘤的女性病例。对肿瘤进行广泛切除,随后采用改良尺骨移位技术重建前臂远端并进行腕关节融合术,术后13年取得了最佳效果且无肿块复发。