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尺骨移位腕关节融合术治疗桡骨远端侵袭性骨巨细胞瘤:短期功能及临床影像学结果

Wrist fusion with ulnar translocation for aggressive giant cell tumour of distal end radius: Short-term functional and clinico-radiological outcomes.

作者信息

Kundu Zile Singh, Sharma PankajKumar, Das Lakshmana, Verma Vishal, Sharma Jyoti

机构信息

Orthopaedics, Positron Multispeciality Hospital, Rohtak, Haryana, 124001, India.

Department of Orthopaedics, All India Institute of Medical Sciences, Bathinda, Punjab, 151001, India.

出版信息

J Orthop. 2024 Sep 26;61:85-91. doi: 10.1016/j.jor.2024.09.018. eCollection 2025 Mar.

Abstract

BACKGROUND

The distal end radius (DER) is the third most common site of a giant cell tumour (GCT) in bone. GCT is a locally aggressive benign tumour with metastatic potential. The main goals in the management of GCT of DER are the complete removal of the tumours, the prevention of recurrence, and the restoration of the functional wrist.

PURPOSE

This case series reports the clinical and functional outcome of en bloc tumour resection, ulnar translocation and wrist arthrodesis in patients with high-grade GCT of DER.

METHODS

Sixteen patients with Campanacci grade II & III GCT of distal end radius who underwent the procedure between 2009 and 2018 and had a follow-up of 2 years were included. Patients with distant metastasis, chronic severe systemic illness, operated previously, and follow-up dropouts were excluded from the study. The patient's demographic profile and tumour characteristics were collected at the initial visit. Grip strength, modified MAYO wrist score, and VAS score for wrist pain were collected preoperatively and at 1-year and 2-year follow-ups.

RESULTS

The study included predominantly females (13 vs 3). The mean age was 31.5 ± 8 years with a symptom duration of 6.5 ± 3.1 months (range 3-14). The mean resection length was 8.31 ± 1.5 cm (range 6-12). The mean Ulnoradial and ulnocarpal union time was 22.7 ± 8.0 and 17.5 ± 2.3 weeks, respectively. The mean modified Mayo Wrist score was 20.63 ± 9.4, 48.7 ± 5.6 and 60.6 ± 4.0 at preop, 1 year and 2 years follow-up. The mean MSTS score was 22.68 ± 1.8 (range 19-26). Two patients had ulnoradial nonunion.

CONCLUSION

Wrist arthrodesis by ulnar translocation and plate fixation is a viable option in the management of GCT of distal end radius. The short-term clinical and functional outcomes are favourable for restoring adequate wrist function.

摘要

背景

桡骨远端是骨巨细胞瘤(GCT)的第三大常见发病部位。骨巨细胞瘤是一种具有转移潜能的局部侵袭性良性肿瘤。桡骨远端骨巨细胞瘤治疗的主要目标是完全切除肿瘤、预防复发以及恢复腕关节功能。

目的

本病例系列报告了桡骨远端高级别骨巨细胞瘤患者行肿瘤整块切除、尺骨移位和腕关节融合术的临床及功能结果。

方法

纳入2009年至2018年间接受该手术且随访2年的16例Campanacci II级和III级桡骨远端骨巨细胞瘤患者。排除有远处转移、慢性严重全身性疾病、既往接受过手术以及失访的患者。在初次就诊时收集患者的人口统计学资料和肿瘤特征。术前以及1年和2年随访时收集握力、改良MAYO腕关节评分以及腕关节疼痛视觉模拟评分(VAS)。

结果

该研究主要纳入女性患者(13例对3例)。平均年龄为31.5±8岁,症状持续时间为6.5±3.1个月(范围3 - 14个月)。平均切除长度为8.31±1.5厘米(范围6 - 12厘米)。尺桡关节和尺腕关节平均愈合时间分别为22.7±8.0周和17.5±2.3周。术前、1年和2年随访时改良MAYO腕关节平均评分分别为20.63±9.4、48.7±5.6和60.6±4.0。肌肉骨骼肿瘤学会(MSTS)平均评分为22.68±1.8(范围19 - 26)。2例患者出现尺桡关节不愈合。

结论

通过尺骨移位和钢板固定进行腕关节融合术是桡骨远端骨巨细胞瘤治疗的一种可行选择。短期临床和功能结果有利于恢复足够的腕关节功能。

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