ME1228的体外和体内研究，ME1228是一种对铜绿假单胞菌具有强效活性的新型肠胃外头孢菌素。
In vitro and in vivo studies of ME1228, a new parenteral cephalosporin with potent activity against Pseudomonas aeruginosa.
作者信息
Miyazaki S, Miyazaki Y, Tsuji A, Nishida M, Goto S
机构信息
Department of Microbiology, Toho University School of Medicine, Tokyo, Japan.
出版信息
Antimicrob Agents Chemother. 1991 Jun;35(6):1245-6. doi: 10.1128/AAC.35.6.1245.
Abstract
The therapeutic effect of ME1228, a new parenteral cephalosporin, was compared with that of broad-spectrum cephems in normal and neutropenic mice infected with various species of bacteria. The results showed that ME1228 was more active than were the other cephems against infections with various pathogens.
摘要
将新型胃肠外头孢菌素ME1228的治疗效果与广谱头孢菌素在感染各种细菌的正常和中性粒细胞减少小鼠中的治疗效果进行了比较。结果表明，ME1228在对抗各种病原体感染方面比其他头孢菌素更具活性。
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本文引用的文献
1
In vitro activity of ME1228, a new parenteral cephalosporin.新型胃肠外头孢菌素ME1228的体外活性
Antimicrob Agents Chemother. 1989 Aug;33(8):1260-7. doi: 10.1128/AAC.33.8.1260.
2
A new aminothiazolylcephalosporin having 1-carboxyethoxyimino group, ME1228.一种具有1-羧基乙氧基亚氨基的新型氨噻唑基头孢菌素，ME1228。
J Antibiot (Tokyo). 1990 Jan;43(1):62-9. doi: 10.7164/antibiotics.43.62.
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