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Rapid response and sustained remission by rituximab in four cases of plasma-exchange-failed acute thrombotic thrombocytopenic purpura.

作者信息

Scaramucci Laura, Niscola Pasquale, Palumbo Roberto, Giovannini Marco, Ales Micaela, Tendas Andrea, Cupelli Luca, Natale Giuseppina, Dentamaro Teresa, Perrotti Alessio Pio, de Fabritiis Paolo

机构信息

Division of Haematology, Sant'Eugenio Hospital, Tor Vergata University, Rome, Italy.

Nephrology Unit, S. Eugenio Hospital, Rome, Italy.

出版信息

Int J Hematol. 2009 Apr;89(3):398-399. doi: 10.1007/s12185-009-0274-9. Epub 2009 Mar 18.

DOI:10.1007/s12185-009-0274-9
PMID:19294484
Abstract
摘要

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1
Rapid response and sustained remission by rituximab in four cases of plasma-exchange-failed acute thrombotic thrombocytopenic purpura.利妥昔单抗治疗4例血浆置换失败的急性血栓性血小板减少性紫癜患者的快速反应及持续缓解
Int J Hematol. 2009 Apr;89(3):398-399. doi: 10.1007/s12185-009-0274-9. Epub 2009 Mar 18.
2
Efficacy of rituximab and concurrent plasma exchange in the treatment of thrombotic thrombocytopenic purpura.利妥昔单抗与同步血浆置换治疗血栓性血小板减少性紫癜的疗效
Clin Adv Hematol Oncol. 2006 Mar;4(3):210-4; discussion 217-8.
3
Remission in acute refractory and relapsing thrombotic thrombocytopenic purpura following rituximab is associated with a reduction in IgG antibodies to ADAMTS-13.利妥昔单抗治疗后，急性难治性和复发性血栓性血小板减少性紫癜的缓解与抗ADAMTS-13 IgG抗体的减少有关。
Br J Haematol. 2007 Feb;136(3):451-61. doi: 10.1111/j.1365-2141.2006.06448.x.
4
Rituximab provided long-term remission in a patient with refractory relapsing thrombotic thrombocytopenic purpura.利妥昔单抗使一名难治性复发性血栓性血小板减少性紫癜患者获得长期缓解。
Int J Hematol. 2005 Jun;81(5):433-6. doi: 10.1532/ijh97.04187.
5
Immunotherapy for thrombotic thrombocytopenic purpura.血栓性血小板减少性紫癜的免疫疗法。
Curr Opin Hematol. 2005 Sep;12(5):359-63. doi: 10.1097/01.moh.0000170534.33517.99.
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Combination of rituximab with therapeutic plasma exchange in a refractory case of thrombotic thrombocytopenic purpura (TTP).利妥昔单抗联合治疗性血浆置换用于治疗一例难治性血栓性血小板减少性紫癜（TTP）。
Transfus Apher Sci. 2013 Oct;49(2):231-3. doi: 10.1016/j.transci.2012.09.007. Epub 2013 Mar 5.
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[Successful treatment with rituximab in a patient with refractory thrombotic thrombocytopenic purpura refractory to plasma exchange].利妥昔单抗成功治疗1例对血浆置换难治的难治性血栓性血小板减少性紫癜患者
Rinsho Ketsueki. 2010 Feb;51(2):127-31.
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Rituximab as preventive therapy of a clinical relapse in TTP with ADAMTS13 inhibitor.利妥昔单抗作为伴有ADAMTS13抑制剂的血栓性血小板减少性紫癜临床复发的预防性治疗。
Am J Hematol. 2007 May;82(5):417-8. doi: 10.1002/ajh.20764.
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Long-term remission in a patient with refractory thrombotic thrombocytopenic purpura treated with rituximab and plasma exchange.利妥昔单抗联合血浆置换治疗难治性血栓性血小板减少性紫癜患者的长期缓解
Ann Hematol. 2008 Apr;87(4):321-3. doi: 10.1007/s00277-007-0384-5. Epub 2007 Sep 27.
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Treatment of acquired thrombotic thrombocytopenic purpura (TTP) with plasma infusion plus rituximab.采用血浆输注联合利妥昔单抗治疗获得性血栓性血小板减少性紫癜（TTP）。
Thromb Haemost. 2008 Jul;100(1):151-3. doi: 10.1160/TH08-02-0089.

本文引用的文献

1
Rituximab as an adjunct to plasma exchange in TTP: a report of 12 cases and review of literature.利妥昔单抗作为血栓性血小板减少性紫癜血浆置换的辅助治疗：12例报告及文献综述
J Clin Apher. 2008;23(5):151-6. doi: 10.1002/jca.20172.
2
Current management of thrombotic thrombocytopenic purpura.血栓性血小板减少性紫癜的当前管理
Curr Opin Hematol. 2008 Sep;15(5):445-50. doi: 10.1097/MOH.0b013e328309ec62.
3
Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura.血管性血友病因子、ADAMTS13与血栓性血小板减少性紫癜
Blood. 2008 Jul 1;112(1):11-8. doi: 10.1182/blood-2008-02-078170.
4
Rituximab for acute plasma-refractory thrombotic thrombocytopenic purpura. A case report and concise review of the literature.利妥昔单抗治疗急性血浆难治性血栓性血小板减少性紫癜：一例报告及文献简要综述
Swiss Med Wkly. 2007 Sep 22;137(37-38):518-24. doi: 10.4414/smw.2007.11908.
5
Targeting the inhibitor of ADAMTS13 in thrombotic thrombocytopenic purpura.
Expert Opin Pharmacother. 2007 Mar;8(4):437-44. doi: 10.1517/14656566.8.4.437.
6
Remission in acute refractory and relapsing thrombotic thrombocytopenic purpura following rituximab is associated with a reduction in IgG antibodies to ADAMTS-13.利妥昔单抗治疗后，急性难治性和复发性血栓性血小板减少性紫癜的缓解与抗ADAMTS-13 IgG抗体的减少有关。
Br J Haematol. 2007 Feb;136(3):451-61. doi: 10.1111/j.1365-2141.2006.06448.x.
7
Rituximab provided long-term remission in a patient with refractory relapsing thrombotic thrombocytopenic purpura.利妥昔单抗使一名难治性复发性血栓性血小板减少性紫癜患者获得长期缓解。
Int J Hematol. 2005 Jun;81(5):433-6. doi: 10.1532/ijh97.04187.
8
Rituximab therapy for refractory thrombotic thrombocytopenic purpura.利妥昔单抗治疗难治性血栓性血小板减少性紫癜
Blood Cells Mol Dis. 2002 May-Jun;28(3):385-91. doi: 10.1006/bcmd.2002.0522.
9
Successful treatment of severe thrombotic thrombocytopenic purpura with the monoclonal antibody rituximab.用单克隆抗体利妥昔单抗成功治疗重症血栓性血小板减少性紫癜。
Am J Hematol. 2002 Oct;71(2):105-8. doi: 10.1002/ajh.10204.