肝癌的影像学检查
Imaging of liver cancer.
作者信息
Ariff Ben, Lloyd Claire R, Khan Sameer, Shariff Mohamed, Thillainayagam Andrew V, Bansi Devinder S, Khan Shahid A, Taylor-Robinson Simon D, Lim Adrian K P
机构信息
Department of Imaging, Imperial College Healthcare NHS Trust, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, United Kingdom.
出版信息
World J Gastroenterol. 2009 Mar 21;15(11):1289-300. doi: 10.3748/wjg.15.1289.
Abstract
Improvements in imaging technology allow exploitation of the dual blood supply of the liver to aid in the identification and characterisation of both malignant and benign liver lesions. Imaging techniques available include contrast enhanced ultrasound, computed tomography and magnetic resonance imaging. This review discusses the application of several imaging techniques in the diagnosis and staging of both hepatocellular carcinoma and cholangiocarcinoma and outlines certain characteristics of benign liver lesions. The advantages of each imaging technique are highlighted, while underscoring the potential pitfalls and limitations of each imaging modality.
摘要
成像技术的进步使得利用肝脏的双重血液供应来辅助识别和表征肝脏良恶性病变成为可能。现有的成像技术包括超声造影、计算机断层扫描和磁共振成像。本综述讨论了几种成像技术在肝细胞癌和胆管癌诊断及分期中的应用，并概述了肝脏良性病变的某些特征。文中突出了每种成像技术的优势，同时强调了每种成像方式潜在的陷阱和局限性。
相似文献
1
Imaging of liver cancer.肝癌的影像学检查
World J Gastroenterol. 2009 Mar 21;15(11):1289-300. doi: 10.3748/wjg.15.1289.
2
Contrast ultrasound LI-RADS LR-5 identifies hepatocellular carcinoma in cirrhosis in a multicenter restropective study of 1,006 nodules.在一项多中心回顾性研究中，1006 个结节的对比超声 LI-RADS LR-5 可识别肝硬化中的肝细胞癌。
J Hepatol. 2018 Mar;68(3):485-492. doi: 10.1016/j.jhep.2017.11.007. Epub 2017 Nov 11.
3
Imaging of combined hepatocellular-cholangiocarcinoma in cirrhosis and risk of false diagnosis of hepatocellular carcinoma.肝硬化中肝细胞癌-胆管细胞癌混合癌的影像学表现与肝细胞癌误诊风险。
United European Gastroenterol J. 2019 Feb;7(1):69-77. doi: 10.1177/2050640618815378. Epub 2018 Nov 22.
4
LI-RADS-CEUS - Proposal for a Contrast-Enhanced Ultrasound Algorithm for the Diagnosis of Hepatocellular Carcinoma in High-Risk Populations.肝脏影像报告和数据系统-超声造影 - 关于高危人群肝细胞癌诊断的超声造影算法提案
Ultraschall Med. 2016 Dec;37(6):627-634. doi: 10.1055/s-0042-112221. Epub 2016 Aug 3.
5
Radiologic imaging and staging of primary and metastatic liver tumors.原发性和转移性肝肿瘤的放射影像学检查与分期
Cancer Treat Res. 2001;109:39-58. doi: 10.1007/978-1-4757-3371-6_3.
6
Characterization of Indeterminate Liver Lesions on CT and MRI With Contrast-Enhanced Ultrasound: What Is the Evidence?CT 和 MRI 平扫联合超声造影对肝脏局灶性病变的定性诊断：有何证据？
AJR Am J Roentgenol. 2020 Jun;214(6):1295-1304. doi: 10.2214/AJR.19.21498. Epub 2020 Mar 17.
7
LI-RADS M (LR-M): definite or probable malignancy, not specific for hepatocellular carcinoma.LI-RADS M（LR-M）：明确或可能为恶性肿瘤，不能特异诊断为肝细胞癌。
Abdom Radiol (NY). 2018 Jan;43(1):149-157. doi: 10.1007/s00261-017-1196-2.
8
Contrast-Enhanced Ultrasound of Focal Liver Lesions.肝脏局灶性病变的超声造影
AJR Am J Roentgenol. 2015 Jul;205(1):W56-66. doi: 10.2214/AJR.14.14203.
9
Interobserver and intermodality agreement of standardized algorithms for non-invasive diagnosis of hepatocellular carcinoma in high-risk patients: CEUS-LI-RADS versus MRI-LI-RADS.高危人群肝细胞癌无创诊断标准化算法的观察者间和模态间一致性：CEUS-LI-RADS 与 MRI-LI-RADS。
Eur Radiol. 2018 Oct;28(10):4254-4264. doi: 10.1007/s00330-018-5379-1. Epub 2018 Apr 19.
10
Imaging diagnosis of colorectal liver metastases.结直肠癌肝转移的影像学诊断。
World J Gastroenterol. 2011 Nov 14;17(42):4654-9. doi: 10.3748/wjg.v17.i42.4654.
引用本文的文献
1
Application of ultrasound in liver cancer from 2014 to 2024: bibliometric analysis and global trends.2014年至2024年超声在肝癌中的应用：文献计量分析与全球趋势
Discov Oncol. 2025 Jul 23;16(1):1395. doi: 10.1007/s12672-025-03177-9.
2
Associations between the SMARS score derived from CT and MRI with histopathological features in HCC.基于CT和MRI得出的SMARS评分与肝癌组织病理学特征之间的关联。
Sci Rep. 2025 Jul 10;15(1):24862. doi: 10.1038/s41598-025-09918-8.
3
Associations between dynamic-contrast enhanced MRI with histopathological features in atypical HCC using spatial co-registration with biopsy.使用活检的空间共配准技术，研究非典型肝癌动态对比增强磁共振成像与组织病理学特征之间的关联。
Am J Transl Res. 2025 Apr 15;17(4):2967-2975. doi: 10.62347/PJYE7877. eCollection 2025.
4
Association between diffusion-weighted imaging and tumor matrix in liver cancer: a cross-sectional study.扩散加权成像与肝癌肿瘤基质之间的关联：一项横断面研究。
Transl Cancer Res. 2025 Mar 30;14(3):1764-1771. doi: 10.21037/tcr-24-1516. Epub 2025 Mar 20.
5
Impact of MRI Texture Analysis on Complication Rate in MRI-Guided Liver Biopsies.MRI纹理分析对MRI引导下肝活检并发症发生率的影响。
J Imaging Inform Med. 2025 Feb 11. doi: 10.1007/s10278-025-01439-0.
6
Enhancing in situ cancer vaccines using delivery technologies.利用递送技术增强原位癌症疫苗。
Nat Rev Drug Discov. 2024 Aug;23(8):607-625. doi: 10.1038/s41573-024-00974-9. Epub 2024 Jul 1.
7
Impact of CT texture analysis on complication rate in CT-guided liver biopsies.CT纹理分析对CT引导下肝活检并发症发生率的影响。
Clin Exp Hepatol. 2024 Mar;10(1):72-78. doi: 10.5114/ceh.2024.134141. Epub 2024 Jan 4.
8
Development of a Reliable GADSAH Model for Differentiating AFP-negative Hepatic Benign and Malignant Occupying Lesions.一种用于鉴别甲胎蛋白阴性肝脏良恶性占位性病变的可靠GADSAH模型的开发
J Hepatocell Carcinoma. 2024 Mar 23;11:607-618. doi: 10.2147/JHC.S452628. eCollection 2024.
9
British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma.英国胃肠病学会胆管癌诊断和管理指南。
Gut. 2023 Dec 7;73(1):16-46. doi: 10.1136/gutjnl-2023-330029.
10
Focal Lesions of the Liver and Radiomics: What Do We Know?肝脏局灶性病变与影像组学：我们了解什么？
Diagnostics (Basel). 2023 Aug 3;13(15):2591. doi: 10.3390/diagnostics13152591.
本文引用的文献
1
Epidemiology, risk factors, and pathogenesis of cholangiocarcinoma.胆管癌的流行病学、危险因素和发病机制。
HPB (Oxford). 2008;10(2):77-82. doi: 10.1080/13651820801992641.
2
Hepatocellular carcinoma: epidemiology, risk factors and pathogenesis.肝细胞癌：流行病学、危险因素与发病机制
World J Gastroenterol. 2008 Jul 21;14(27):4300-8. doi: 10.3748/wjg.14.4300.
3
Hilar cholangiocarcinoma: MRI/MRCP in staging and treatment planning.肝门部胆管癌：MRI/MRCP在分期及治疗规划中的应用
Abdom Imaging. 2008 Jul-Aug;33(4):444-51. doi: 10.1007/s00261-007-9281-6.
4
Abdominal MRI advances in the detection of liver tumours and characterisation.腹部磁共振成像在肝脏肿瘤检测及特征描述方面取得进展。
Lancet Oncol. 2007 Jun;8(6):525-35. doi: 10.1016/S1470-2045(07)70170-5.
5
High-resolution computed tomography accurately predicts resectability in hilar cholangiocarcinoma.高分辨率计算机断层扫描能准确预测肝门部胆管癌的可切除性。
Am J Surg. 2007 Jun;193(6):702-6. doi: 10.1016/j.amjsurg.2006.10.024.
6
Hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: helical CT and MR imaging findings with clinical-pathologic comparison.非酒精性脂肪性肝病患者的肝细胞癌：螺旋CT及MR成像表现与临床病理对照
Radiology. 2007 May;243(2):422-30. doi: 10.1148/radiol.2432051244. Epub 2007 Mar 13.
7
Hepatobiliary MRI: current concepts and controversies.肝胆磁共振成像：当前概念与争议
J Magn Reson Imaging. 2007 Apr;25(4):681-95. doi: 10.1002/jmri.20844.
8
Gadolinium-based MR contrast agents and nephrogenic systemic fibrosis.钆基磁共振造影剂与肾源性系统性纤维化
Radiology. 2007 Mar;242(3):647-9. doi: 10.1148/radiol.2423061640. Epub 2007 Jan 9.
9
Phagocytosis of ultrasound contrast agent microbubbles by Kupffer cells.库普弗细胞对超声造影剂微泡的吞噬作用。
Ultrasound Med Biol. 2007 Feb;33(2):318-25. doi: 10.1016/j.ultrasmedbio.2006.08.008.
10
Dynamic FDG-PET is useful for detection of cholangiocarcinoma in patients with PSC listed for liver transplantation.动态氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）对于检测列入肝移植名单的原发性硬化性胆管炎（PSC）患者的胆管癌很有用。
Hepatology. 2006 Dec;44(6):1572-80. doi: 10.1002/hep.21433.
Zotero 插件