Yang Hong-Jun, Tang Shi-Huan, Huang Lu-Qi, Xiao Pei-Gen
Institute of Chinese Material Medica, China Academy of Chinese Medical sciences, Beijing 100700, China.
Zhongguo Zhong Yao Za Zhi. 2008 Dec;33(24):2983-5.
In this paper, based on analyzing the status quo and key problem of research on nature of Chinese materia medica, we propose the thinking of research on nature of Chinese materia medica in view of genetic relationship. Namely, according to the cue of documents arrangement and data excavation, in certern scope of genetic relationship, difinite the common pharmaco-effect of the same nature of drug, and analyze the chemical composition correlated the nature of drug, further more, reveal the related regularity of nature of Chinese materia medica-pharmaco-effect- chemical composition. Linking the nature of Chinese materia medica, pharmaco-effect and chemical composition will provide original thinking and view angle to break through the key problem of research on nature of Chinese materia medica.
本文在分析中药药性研究现状及关键问题的基础上,从亲缘关系角度提出中药药性研究思路。即依据文献整理与数据挖掘线索,在一定亲缘关系范围内,明确同一药性药物的共同药理效应,分析与药性相关的化学成分,进而揭示中药药性-药理效应-化学成分的相关规律。将中药药性、药理效应与化学成分相联系,可为突破中药药性研究的关键问题提供原创性思路与视角。