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一项强化行为减肥干预随机对照试验中,超重和肥胖尿失禁女性的性功能情况。

Sexual function among overweight and obese women with urinary incontinence in a randomized controlled trial of an intensive behavioral weight loss intervention.

作者信息

Huang Alison J, Stewart Anita L, Hernandez Alexandra L, Shen Hui, Subak Leslee L

机构信息

Department of Medicine, University of California, San Francisco, San Francisco, California, USA.

出版信息

J Urol. 2009 May;181(5):2235-42. doi: 10.1016/j.juro.2009.01.046. Epub 2009 Mar 17.

Abstract

PURPOSE

We examined sexual function in overweight and obese women with urinary incontinence, and evaluated the effects of an intensive behavioral weight reduction intervention on sexual function in this population.

MATERIALS AND METHODS

A total of 338 overweight and obese women reporting 10 or more incontinence episodes weekly were randomized to an intensive behavioral change (226) or structured education program (112) for 6 months. Sexual function was assessed using self-administered questionnaires. Multivariate regression was used to examine factors associated with baseline and 6-month change in sexual function as well as intervention effects.

RESULTS

Two-thirds of participants (233) were sexually active at baseline but more than half (188) reported low desire and a quarter (91) were sexually dissatisfied. More than half of sexually active participants (123) reported problems with arousal, lubrication, orgasm or incontinence during sex. Compared to controls women in the intervention group demonstrated a borderline increase in frequency of sexual activity at 6 months (OR 1.34, 95% CI 0.99-1.81, p = 0.06) but no differences in satisfaction (OR 1.28, 95% CI 0.83-1.99, p = 0.26), desire (OR 1.12, 95% CI 0.79-1.61, p = 0.52) or problems (beta +/- SE 0.03 +/- 0.07, p = 0.68 for intervention effects on problems score). Neither clinical incontinence severity nor body mass index was independently associated with baseline or 6-month change in function (p >0.10 for all).

CONCLUSIONS

Sexual dysfunction is common in overweight and obese women with incontinence but the severity of this dysfunction may not be directly related to the severity of incontinence or obesity. An intensive 6-month behavioral weight reduction intervention did not significantly improve sexual function in this population relative to controls.

摘要

目的

我们研究了患有尿失禁的超重和肥胖女性的性功能,并评估了强化行为减肥干预对该人群性功能的影响。

材料与方法

共有338名每周报告10次或更多尿失禁发作的超重和肥胖女性被随机分为强化行为改变组(226名)或结构化教育组(112名),为期6个月。使用自我管理问卷评估性功能。多变量回归用于检查与性功能基线和6个月变化相关的因素以及干预效果。

结果

三分之二的参与者(233名)在基线时具有性活动,但超过一半(188名)报告性欲低下,四分之一(91名)对性生活不满意。超过一半的性活跃参与者(123名)报告在性交过程中存在性唤起、润滑、性高潮或尿失禁问题。与对照组相比,干预组女性在6个月时的性活动频率有临界增加(OR 1.34,95%CI 0.99 - 1.81,p = 0.06),但在满意度(OR 1.28,95%CI 0.83 - 1.99,p = 0.26)、性欲(OR 1.12,95%CI 0.79 - 1.61,p = 0.52)或问题方面无差异(干预对问题评分的效应β +/- SE 0.03 +/- 0.07,p = 0.68)。临床尿失禁严重程度和体重指数均与功能的基线或6个月变化无独立相关性(所有p > 0.10)。

结论

性功能障碍在患有尿失禁的超重和肥胖女性中很常见,但这种功能障碍的严重程度可能与尿失禁或肥胖的严重程度没有直接关系。相对于对照组,为期6个月的强化行为减肥干预并未显著改善该人群的性功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/2744348/7e7682d646f4/nihms-129634-f0001.jpg

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