《阴道衰老日常影响问卷》：一项关于绝经后女性阴道症状对其功能和幸福感影响的多维测量。
Day-to-Day Impact of Vaginal Aging questionnaire: a multidimensional measure of the impact of vaginal symptoms on functioning and well-being in postmenopausal women.
作者信息
Huang Alison J, Gregorich Steven E, Kuppermann Miriam, Nakagawa Sanae, Van Den Eeden Stephen K, Brown Jeanette S, Richter Holly E, Walter Louise C, Thom David, Stewart Anita L
机构信息
From the Departments of 1Medicine and 2Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, CA; 3Division of Research, Kaiser Permanente, Oakland, CA; 4Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL; and 5Department of Family and Community Medicine and 6Institute of Health and Aging, University of California San Francisco, San Francisco, CA.
出版信息
Menopause. 2015 Feb;22(2):144-54. doi: 10.1097/GME.0000000000000281.
OBJECTIVE
This study aims to develop a self-report questionnaire assessing the impact of vaginal dryness, soreness, itching, irritation, and pain on functioning and well-being in postmenopausal women.
METHODS
Structured self-report items were developed to address the impact of vaginal symptoms on functioning and well-being based on findings from focus groups with racially/ethnically diverse, symptomatic postmenopausal women. Items were refined after cognitive interview pretesting and field-tested among symptomatic postmenopausal women enrolled in a multiethnic cohort study in California. Exploratory factor analysis (SAS PROC VARCLUS) and confirmatory factor analysis evaluated factor structure and eliminated poorly fitting items. Additional evidence of construct validity was obtained via examination of correlations with other measures of related constructs. Internal consistency and test-retest reliability were assessed using Cronbach α and correlation coefficients, respectively.
RESULTS
For the 745 postmenopausal women who completed the draft questionnaire, the mean (SD) age was 56.2 (8.5) years, and 66% of the respondents were racial/ethnic minorities. The refined questionnaire included four multi-item scales addressing symptom impact on (1) activities of daily living, (2) emotional well-being, (3) sexual functioning, and (4) self-concept and body image. The four-factor model provided good approximate fit (comparative fit index, 0.987; standardized root-mean-square residual, 0.038). Correlations with other measures of symptom bothersomeness, sexual function, depression, and anxiety conformed to hypotheses. Cronbach α values ranged from 0.82 to 0.93. Intraclass coefficients ranged from 0.47 to 0.72.
CONCLUSIONS
The Day-to-Day Impact of Vaginal Aging questionnaire is a new multidimensional self-report measure designed to facilitate evaluation of the impact of vaginal symptoms on postmenopausal women of diverse backgrounds.
目的
本研究旨在开发一份自我报告问卷，以评估阴道干燥、酸痛、瘙痒、刺激和疼痛对绝经后女性功能和幸福感的影响。
方法
根据对不同种族/民族、有症状的绝经后女性焦点小组的研究结果，制定结构化的自我报告项目，以解决阴道症状对功能和幸福感的影响。在认知访谈预测试后对项目进行了完善，并在加利福尼亚州一项多民族队列研究中纳入的有症状绝经后女性中进行了现场测试。探索性因素分析（SAS PROC VARCLUS）和验证性因素分析评估了因素结构并剔除了拟合不佳的项目。通过检查与相关结构的其他测量指标的相关性，获得了结构效度的额外证据。分别使用Cronbach α系数和相关系数评估内部一致性和重测信度。
结果
对于完成问卷初稿的745名绝经后女性，平均（标准差）年龄为56.2（8.5）岁，66%的受访者为种族/民族少数群体。完善后的问卷包括四个多项目量表，涉及症状对（1）日常生活活动、（2）情绪幸福感、（3）性功能以及（4）自我概念和身体形象的影响。四因素模型提供了良好的近似拟合（比较拟合指数，0.987；标准化均方根残差，0.038）。与症状困扰、性功能、抑郁和焦虑的其他测量指标的相关性符合假设。Cronbach α值范围为0.82至0.93。组内相关系数范围为0.47至0.72。
结论
阴道衰老的日常影响问卷是一种新的多维自我报告测量工具，旨在便于评估阴道症状对不同背景绝经后女性的影响。
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