Giannini F, Passero S, Cioni R, Paradiso C, Battistini N, Giordano N, Vaccai D, Marcolongo R
Institute for Nervous and Mental Diseases, University of Siena, Italy.
Arch Phys Med Rehabil. 1991 Sep;72(10):738-42.
Extensive sensory and motor nerve conduction studies were performed in a series of patients with electrophysiologically proven, idiopathic carpal tunnel syndrome who were treated by a single steroid injection (40 mg of triamcinolone acetonide). Electrophysiologic studies, which included evaluation of median, ulnar, and radial orthodromic sensory action potentials, median and ulnar motor action potentials, and electromyography of two intrinsic muscles of the hand, were done before and at 45 days and six months after the treatment. By the end of the follow-up period, the symptoms had remitted completely in 11 hands (35%), 18 (58%) benefitted from partial relief, and two did not improve. In addition to the relief of symptoms, abnormalities of motor nerve conduction improved in 65% of cases, and abnormalities of sensory nerve conduction improved in 73% of all the individual digital branches of the median nerve examined. Recovery of function of the median nerve continued for a long period, even after the pharmacologic effect of the steroid agent had presumably ceased.
对一系列经电生理证实为特发性腕管综合征且接受单次类固醇注射（40毫克曲安奈德）治疗的患者进行了广泛的感觉和运动神经传导研究。在治疗前、治疗后45天和6个月进行了电生理研究，包括评估正中神经、尺神经和桡神经的顺向感觉动作电位、正中神经和尺神经运动动作电位以及手部两块固有肌的肌电图。到随访期结束时，11只手（35%）症状完全缓解，18只手（58%）部分缓解，2只手无改善。除症状缓解外，65%的病例运动神经传导异常得到改善，在所有检测的正中神经各指分支中，73%的感觉神经传导异常得到改善。即使类固醇药物的药理作用可能已经消失，正中神经功能的恢复仍持续了很长一段时间。
