Kawa Gen, Taniguchi Hisanori, Kinoshita Hidefumi, Matsuda Tadashi
The Department of Urology and Andrology, Kansai Medical University.
Hinyokika Kiyo. 2009 Feb;55(2):87-92.
A specialized clinic for middle-aged and elderly hypogonadal men was established in our institution five years ago. A retrospective study of the 511 patients who attended our clinic during this period was conducted and the issues involved in treating these patients were identified. The patients' age distribution, symptoms, serum testosterone values, treatment, and course were examined. The patients' mean age was 54.0 years (range, 35 to 74 years); approximately half of the patients were in their fifties. Most patients complained of decline in libido, general fatigue, and erectile dysfunction. The patients' mean serum free testosterone was 9.28 pg/ml; 40.3% of patients had a serum free testosterone value of less than 8.5 pg/ml, which is the threshold value for the initiation of androgen replacement therapy (ART) in Japan. ART was given to 220 (43.1%) patients, and it was considered effective in 100. It appears that male climacteric disorder and late-onset hypogonadism have become commonly recognized in Japan. There will be an increasing need for specialized clinics for such men in the future.
五年前，我们机构设立了一家针对中老年性腺功能减退男性的专科诊所。对这期间前来我们诊所就诊的511例患者进行了回顾性研究，并确定了治疗这些患者所涉及的问题。对患者的年龄分布、症状、血清睾酮值、治疗情况及病程进行了检查。患者的平均年龄为54.0岁（范围35至74岁）；约一半患者为五十多岁。大多数患者主诉性欲减退、全身乏力及勃起功能障碍。患者的平均血清游离睾酮为9.28 pg/ml；40.3%的患者血清游离睾酮值低于8.5 pg/ml，这是日本启动雄激素替代疗法（ART）的阈值。220例（43.1%）患者接受了ART治疗，其中100例被认为有效。在日本，男性更年期综合征和迟发性性腺功能减退似乎已得到普遍认可。未来，此类男性对专科诊所的需求将不断增加。
