Srivastava Vijay, Mandhan Parkash, Pringle Kevin, Morreau Philip, Beasley Spencer, Samarakkody Udaya
Department of Pediatric Surgery, Waikato Hospital, Hamilton 2240, New Zealand.
J Pediatr Surg. 2009 Mar;44(3):551-5. doi: 10.1016/j.jpedsurg.2008.09.025.
An apparent increase in the incidence of gastroschisis and exomphalos has been reported from several parts of the world. The exact mechanism of this trend is unknown. The aim of this study was to determine the regional and national trends in the incidence of gastroschisis and exomphalos in New Zealand.
This retrospective multicenter study involved collection of data from all 4 tertiary care pediatric surgical centers in New Zealand. The incidence was calculated per 10,000 live births. Data were analyzed to determine the regional and national trends. The statistical analysis was done using linear regression model and Poisson distribution.
The incidence of gastroschisis has increased from 2.96 per 10,000 live births to 5.16 per 10,000 live births between 1996 and 2004. During the same period, the incidence of exomphalos has increased from 0.69 per 10,000 live births to 3.27 per 10,000 live births. Gastroschisis was observed more in younger mothers, whereas exomphalos was associated with older mothers.
The incidence of gastroschisis and exomphalos is increasing in New Zealand, which is consistent with worldwide trends in showing the increasing incidence of anterior abdominal wall defects.
世界上多个地区报告称腹裂和脐膨出的发病率明显上升。这种趋势的确切机制尚不清楚。本研究的目的是确定新西兰腹裂和脐膨出发病率的地区和全国趋势。
这项回顾性多中心研究涉及从新西兰所有4个三级护理儿科手术中心收集数据。发病率按每10000例活产计算。对数据进行分析以确定地区和全国趋势。使用线性回归模型和泊松分布进行统计分析。
1996年至2004年间，腹裂的发病率从每10000例活产2.96例增加到每10000例活产5.16例。在同一时期，脐膨出的发病率从每10000例活产0.69例增加到每10000例活产3.27例。腹裂在年轻母亲中更为常见，而脐膨出与年长母亲有关。
新西兰腹裂和脐膨出的发病率正在上升，这与全球前腹壁缺陷发病率上升的趋势一致。
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