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[肺误吸:流行病学与危险因素]

[Pulmonary aspiration: epidemiology and risk factors].

作者信息

Landreau B, Odin I, Nathan N

机构信息

Département d'anesthésie-réanimation chirurgicale, hôpital Mère-Enfant, avenue du Dr-D.-Larrey, Limoges cedex, France.

出版信息

Ann Fr Anesth Reanim. 2009 Mar;28(3):206-10. doi: 10.1016/j.annfar.2009.01.020. Epub 2009 Mar 21.

Abstract

OBJECTIVE

To determine the epidemiology and risk factors for gastric aspiration in a French university hospital.

METHODS

Files were prospectively selected from a computer database of rare and severe complications between January 2002 et April 2007. Medical files were then analyzed according to a predetermined list of specific items.

RESULTS

Forty patients suffered from gastric aspiration among 117 033 anaesthesias (4 medical files lost) (31/100,000 global incidence). All occurred during general anaesthesia, 83% at induction, 8% in the recovery room, half of the cases for emergent cases (15% of emergency). In emergency, the incidence of gastric aspiration increased by 4.5. Only 14 patients (39%) had a "full stomach", 17 (47%) other risk factors and five (14%) none. A rapid induction-intubation sequence with a Sellick manoeuvre was performed in only 50% of patients with a full stomach and in 23.6% of those with other risk factors. Gastric aspiration occurred in three patients with a laryngeal mask. Aspiration was associated with clinical symptoms in 21 patients. Eleven patients developed an ARDS (5 deaths).

DISCUSSION

The incidence of gastric aspiration was slightly higher in this series than in other published series. Rapid induction-intubation sequence with Sellick manoeuvre is not always used in patients with a full stomach. Restraining this technique only to these latter patients does not guarantee practitioners to avoid the risk of gastric aspiration. There is a large need to define which patients are at higher risk of gastric aspiration by national recommendations of clinical practice.

摘要

目的

确定一家法国大学医院胃内容物误吸的流行病学特征及危险因素。

方法

从2002年1月至2007年4月间的罕见及严重并发症计算机数据库中前瞻性选取病例档案。然后根据预先确定的特定项目清单对医疗档案进行分析。

结果

在117033例麻醉中,有40例发生胃内容物误吸(4份病历丢失)(总发生率为31/100,000)。所有误吸均发生在全身麻醉期间,83%发生在诱导期,8%发生在恢复室,半数病例为急诊手术(急诊手术的15%)。在急诊手术中,胃内容物误吸的发生率增加了4.5倍。只有14例患者(39%)为“饱胃”,17例(47%)有其他危险因素,5例(14%)无危险因素。仅50%的饱胃患者和23.6%有其他危险因素的患者进行了快速诱导插管并实施了Sellick手法。3例使用喉罩的患者发生了胃内容物误吸。21例患者的误吸伴有临床症状。11例患者发生急性呼吸窘迫综合征(5例死亡)。

讨论

本系列中胃内容物误吸的发生率略高于其他已发表系列。饱胃患者并非总是采用快速诱导插管并实施Sellick手法。仅对后者采用该技术并不能保证从业者避免胃内容物误吸的风险。非常有必要通过国家临床实践指南来明确哪些患者胃内容物误吸风险更高。

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