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药品专利期限对加拿大研发及药品支出的影响。

The effect of pharmaceutical patent term length on research and development and drug expenditures in Canada.

作者信息

Grootendorst Paul, Matteo Livio Di

机构信息

Faculty of Pharmacy, University of Toronto, Toronto, ON.

出版信息

Healthc Policy. 2007 Feb;2(3):63-84.

Abstract

While pharmaceutical patent terms have increased in Canada, increases in patented drug spending have been mitigated by price controls and retrenchment of public prescription drug subsidy programs. We estimate the net effects of these offsetting policies on domestic pharmaceutical R&D expenditures and also provide an upper-bound estimate on the effects of these policies on Canadian pharmaceutical spending over the period 1988-2002. We estimate that R&D spending increased by $4.4 billion (1997 dollars). Drug spending increased by $3.9 billion at most and, quite likely, by much less. Cutbacks to public drug subsidies and the introduction of price controls likely mitigated drug spending growth. In cost-benefit terms, we suspect that the patent extension policies have been beneficial to Canada.

摘要

虽然加拿大的药品专利期限有所延长,但专利药品支出的增长因价格管制和公共处方药补贴计划的缩减而得到缓解。我们估算了这些抵消政策对国内制药研发支出的净影响,并对这些政策在1988 - 2002年期间对加拿大药品支出的影响给出了上限估计。我们估计研发支出增加了44亿美元(按1997年美元计算)。药品支出最多增加了39亿美元,而且很可能远低于此。公共药品补贴的削减和价格管制的实施可能减缓了药品支出的增长。从成本效益角度来看,我们怀疑专利延期政策对加拿大是有益的。

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