den Dunnen Johan T, Sijmons Rolf H, Andersen Paal S, Vihinen Mauno, Beckmann Jacques S, Rossetti Sandro, Talbot C Conover, Hardison Ross C, Povey Sue, Cotton Richard G H
Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands.
Hum Mutat. 2009 Apr;30(4):493-5. doi: 10.1002/humu.20977.
Several Locus-Specific DataBases (LSDBs) have recently been approached by larger, more general data repositories (including NCBI and UCSC) with the request to share the DNA variant data they have collected. Within the Human Genome Variation Society (HGVS) a document was generated summarizing the issues related to these requests. The document has been circulated in the HGVS/LSDB community and was discussed extensively. Here we summarize these discussions and present the concluded recommendations for LSDB data sharing with central repositories.
最近，一些较大的、更通用的数据存储库（包括美国国家生物技术信息中心和加州大学圣克鲁兹分校）与几个特定基因座数据库（LSDBs）接洽，要求分享它们收集的DNA变异数据。人类基因组变异协会（HGVS）内部编写了一份文件，总结了与这些请求相关的问题。该文件已在HGVS/LSDB社区中传阅并进行了广泛讨论。在此，我们总结这些讨论内容，并提出关于LSDB与中央存储库数据共享的最终建议。
