Saeki Naokatsu, Murai Hisayuki, Hasegawa Yuzo, Horiguchi Kentaro, Hanazawa Toyoyuki, Fukuda Kazumasa
Department of Neurosurgery, Chiba University Graduate School of Medicine, Chiba-City, Chiba 260-8670, Japan.
No Shinkei Geka. 2009 Mar;37(3):229-46.
Endoscopic endonasal transsphenoidal surgery has been performed because of its advantages such as less invasive surgical management and more aggressive tumor removal of extrasellar lesions. In 2003, we began endoscope-assisting surgery. In 2006, we completely switched to the endoscopic endonasal approach without microscope or nasal specula. Today, we report endoscopic pituitary and skull base surgery in our institute. The endonasal approach via the sphenoid ostium was carried out without nasal specula. Postoperative nasal packing was basically not needed in such cases. In cases with meningiomas, craniopharyngiomas and giant pituitary adenomas, which needed intra-dural procedure, nasal procedures such as middle nasal conchotomy, posterior ethmoidectomy and skull base techniques such as optic canal decompression and removal of the planum sphenoidale were carried out to gain the wider operative field toward anterior skull base and lower clivus. Navigation and US-Doppler were essential. Angled endoscope attained more successful removal of tumor under direct visualization extending into the cavernous sinus (GH secreting ademomas) and lower clivus (chordoma). In the case of CSF (cerebrospinal fluid) leakage during operation, a newly designed balloon catheter was placed in the sphenoid sinus to fix the abdominal fat and fibrin glue at the leakage point. In recent cases, dural opening has been sutured. In the combination of such techniques, a lumbar drainage system to prevent postoperative CSF rhinorrhea became needless in many cases. Angled suction tips, single-shaft coagulation tools and slim and longer holding forceps, all of which were newly designed for endoscopic surgery, were essential for smoother procedure. Endonasal endoscopic pituitary surgery has resulted in less invasive transsphenoidal surgery since no postoperative nasal packing is needed and there is less dependency on lumbar drainage. Although better techniques to prevent postoperative CSF leakage needs to be developed, this endoscopic pituitary surgery will become more common and will become a standard procedure. Endoscopic skull base surgery has enabled more aggressive removal of extrasellar tumors with the aid of nasal and skull base techniques. This endoscopic skull base surgery is more highly specialized, needs special techniques and surgical training. Selection of patients is also important. This also needs collaboration with ENT (ear, nose, throat) doctors. To be acknowledged as a safe and successful procedure in skull base surgery, this complex procedure may be preferably carried out only in center hospitals, which deal with many patients with a skull base lesion.
鼻内镜下经蝶窦手术因其具有侵袭性较小的手术管理及能更积极地切除鞍外病变等优势而得以开展。2003年,我们开始进行内镜辅助手术。2006年,我们完全转向了不使用显微镜或鼻窥器的鼻内镜入路。如今,我们报告我院的鼻内镜下垂体及颅底手术情况。经蝶窦开口的鼻内镜入路在不使用鼻窥器的情况下进行。此类病例基本无需术后鼻腔填塞。对于需要进行硬膜内手术的脑膜瘤、颅咽管瘤及巨大垂体腺瘤病例,需进行如中鼻甲切除术、后筛窦切除术等鼻腔手术以及如视神经管减压和蝶骨平台切除等颅底手术,以获得朝向颅前窝底和下斜坡更广阔的手术视野。导航和超声多普勒至关重要。成角内镜在直视下能更成功地切除延伸至海绵窦(生长激素分泌性腺瘤)和下斜坡(脊索瘤)的肿瘤。手术过程中若发生脑脊液漏,可在蝶窦内放置一种新设计的球囊导管,以在漏口处固定腹部脂肪和纤维蛋白胶。在近期的病例中,硬膜开口已进行缝合。在这些技术的联合应用下,许多病例无需腰大池引流系统来预防术后脑脊液鼻漏。成角吸引头、单轴凝血工具以及细长的持钳,所有这些都是专门为内镜手术新设计的,对于手术的顺利进行至关重要。鼻内镜下垂体手术已成为侵袭性较小的经蝶窦手术,因为无需术后鼻腔填塞且对腰大池引流的依赖较小。尽管需要开发更好的预防术后脑脊液漏的技术,但这种鼻内镜下垂体手术将变得更为常见并成为一种标准术式。鼻内镜下颅底手术借助鼻腔和颅底技术能够更积极地切除鞍外肿瘤。这种鼻内镜下颅底手术专业性更强,需要特殊技术和手术培训。患者的选择也很重要。这还需要与耳鼻喉科医生合作。为了在颅底手术中被认可为一种安全且成功的手术,这种复杂手术可能最好仅在处理众多颅底病变患者的中心医院开展。