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肝门部胆管癌的门静脉栓塞术

Portal vein embolization in hilar cholangiocarcinoma.

作者信息

Palavecino Martin, Abdalla Eddie K, Madoff David C, Vauthey Jean-Nicolas

机构信息

Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 444, Houston, TX 77030, USA.

出版信息

Surg Oncol Clin N Am. 2009 Apr;18(2):257-67, viii. doi: 10.1016/j.soc.2008.12.007.

Abstract

In patients with hilar cholangiocarcinoma, extended hepatectomy and caudate lobe resection are often performed to achieve an R0 resection. In patients whose standardized future liver remnant is less than or equal to 20% of total liver volume, portal vein embolization (PVE) should be performed. In patients with biliary dilatation of the future liver remnant, a biliary drainage catheter should be placed before PVE. If the planned surgery is an extended right hepatectomy, segment 4 branch embolization improves the hypertrophy of segments 2 and 3. In high-volume centers, PVE can be safely performed; it increases the resectability rate and results in the same survival rates as those in patients who undergo resection without PVE.

摘要

对于肝门部胆管癌患者,常进行扩大肝切除术和尾状叶切除术以实现R0切除。对于标准未来肝剩余体积小于或等于全肝体积20%的患者,应进行门静脉栓塞(PVE)。对于未来肝剩余存在胆管扩张的患者,应在PVE前放置胆管引流导管。如果计划手术为扩大右肝切除术,对4段分支进行栓塞可促进2段和3段的肥大。在大型医疗中心,可以安全地进行PVE;它可提高可切除率,并且与未进行PVE而接受切除术的患者生存率相同。

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