老年人的休闲活动与血管性认知障碍风险
Leisure activities and risk of vascular cognitive impairment in older adults.
作者信息
Verghese Joe, Katz Mindy J, Sanders Amy, Lipton Richard B
机构信息
Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
出版信息
J Geriatr Psychiatry Neurol. 2009 Jun;22(2):110-8. doi: 10.1177/0891988709332938. Epub 2009 Mar 23.
Abstract
"Vascular cognitive impairment'' refers to cognitive impairment caused or associated with vascular risk factors, and encompasses a cognitive spectrum ranging from mild cognitive impairment to dementia. We examined the association of leisure activity participation to risk of developing VCI in the Bronx aging study. Over 21 years, 71 of the 401 participants who were free of dementia or VCI at entry developed VCI (49 participants with VCI without dementia). We derived Cognitive and Physical Activity Scales based on frequency of leisure activity participation. A 1-point increase on the Cognitive, but not Physical Activity Scale, was associated with lower risk of VCI (hazard ratio 0.931, 95% confidence interval [CI] 0.895-0.970) in Cox analysis. Participation in cognitive but not physical leisure activities is associated with lower risk of VCI with or without dementia. Prospective studies and clinical trials are needed to define the causal role of cognitive leisure activities in influencing vascular risk for cognitive decline.
摘要
“血管性认知障碍”指由血管危险因素引起或与之相关的认知障碍，涵盖从轻度认知障碍到痴呆的一系列认知情况。在布朗克斯衰老研究中，我们研究了休闲活动参与情况与发生血管性认知障碍风险之间的关联。在21年的时间里，401名入组时无痴呆或血管性认知障碍的参与者中有71人患上了血管性认知障碍（49名参与者患有无痴呆的血管性认知障碍）。我们根据休闲活动参与频率得出了认知和身体活动量表。在Cox分析中，认知活动量表上增加1分与血管性认知障碍风险降低相关（风险比0.931，95%置信区间[CI] 0.895 - 0.970），而身体活动量表则不然。参与认知性而非身体性休闲活动与患或未患痴呆的血管性认知障碍风险降低相关。需要进行前瞻性研究和临床试验来确定认知性休闲活动在影响认知衰退血管风险方面的因果作用。
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本文引用的文献
1
How do heart disease and stroke become risk factors for Alzheimer's disease?心脏病和中风是如何成为阿尔茨海默病的风险因素的？
Neurol Res. 2006 Sep;28(6):637-44. doi: 10.1179/016164106X130362.
2
Experience-driven brain plasticity: beyond the synapse.经验驱动的大脑可塑性：超越突触
Neuron Glia Biol. 2004 Nov;1(4):351-63. doi: 10.1017/s1740925x05000219.
3
National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards.美国国立神经疾病与中风研究所-加拿大中风网络血管性认知障碍协调标准
Stroke. 2006 Sep;37(9):2220-41. doi: 10.1161/01.STR.0000237236.88823.47. Epub 2006 Aug 17.
4
Exercise, cognition, and the aging brain.运动、认知与衰老的大脑。
J Appl Physiol (1985). 2006 Oct;101(4):1237-42. doi: 10.1152/japplphysiol.00500.2006. Epub 2006 Jun 15.
5
On neural plasticity, new neurons and the postischemic milieu: an integrated view on experimental rehabilitation.论神经可塑性、新生神经元与缺血后环境：实验性康复的综合观点
Exp Neurol. 2006 May;199(1):42-55. doi: 10.1016/j.expneurol.2006.03.010. Epub 2006 Apr 24.
6
Leisure activities and the risk of amnestic mild cognitive impairment in the elderly.老年人的休闲活动与遗忘型轻度认知障碍风险
Neurology. 2006 Mar 28;66(6):821-7. doi: 10.1212/01.wnl.0000202520.68987.48. Epub 2006 Feb 8.
7
Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older.运动与65岁及以上人群患痴呆症的风险降低有关。
Ann Intern Med. 2006 Jan 17;144(2):73-81. doi: 10.7326/0003-4819-144-2-200601170-00004.
8
Participation in novelty-seeking leisure activities and Alzheimer's disease.参与寻求新奇的休闲活动与阿尔茨海默病
J Geriatr Psychiatry Neurol. 2005 Sep;18(3):134-41. doi: 10.1177/0891988705277537.
9
Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice.环境富集可降低转基因小鼠的β-淀粉样蛋白水平及淀粉样蛋白沉积。
Cell. 2005 Mar 11;120(5):701-13. doi: 10.1016/j.cell.2005.01.015.
10
The pattern of neuropsychological deficits in Vascular Cognitive Impairment-No Dementia (Vascular CIND).血管性认知障碍无痴呆（Vascular CIND）的神经心理学缺陷模式。
Clin Neuropsychol. 2004 Feb;18(1):41-9. doi: 10.1080/13854040490507145.
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