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睾丸癌男性患者医嘱依从性预测因素的前瞻性研究。

Prospective study of factors predicting adherence to medical advice in men with testicular cancer.

作者信息

Moynihan Clare, Norman Andy R, Barbachano Yolanda, Burchell Louise, Huddart Robert, Dearnaley David P, Horwich Alan

机构信息

Academic Radiotherapy Unit, The Institute of Cancer Research and Department of Clinical Research Development, Royal Marsden National Health Service Foundation Trust, Sutton, Surrey, United Kingdom.

出版信息

J Clin Oncol. 2009 May 1;27(13):2144-50. doi: 10.1200/JCO.2008.16.1901. Epub 2009 Mar 23.

Abstract

PURPOSE

To identify predictive factors of adherence to medical advice, specifically the likelihood of attendance to a recommended follow-up regimen in patients with newly diagnosed testicular cancer. PATIENTS AND METHODS; This was a prospective study measuring initially not only aspects of the doctor-patient interview, but also a range of demographic, psychological, social, and medical factors, and then recording attendance behavior on follow-up. All 209 new patients with testicular cancer referred between June 1992 and May 1995 were approached, and 184 men consented and completed questionnaires. The nonadherence end point (nonattender) was two failures to attend an outpatient appointment at least 1 month apart, despite a written reminder.

RESULTS

Thirty-two participants (17%) were classified as nonattenders. No significant differences were found between attenders and nonattenders in the majority of psychosocial and medical variables that might have predicted nonadherence to medical advice. There was a highly significant association between nonattendance and a patient's perception of an unsatisfactory affective relationship with his clinician (P = .005; hazard ratio, 3.1; 95% CI, 1.4 to 6.6).

CONCLUSION

Patients who perceived an unsatisfactory affective relationship with their clinician that included an inability to trust the clinician and a perception that they were not being treated as "a person" were subsequently more likely to disregard medical advice regarding follow-up. Attention to the ways young men may wish to communicate with their clinicians is important, bearing in mind that they may not necessarily adhere to stereotypical images of masculine self-dependence.

摘要

目的

确定遵循医嘱的预测因素,特别是新诊断出的睾丸癌患者接受推荐的后续治疗方案的可能性。患者与方法:这是一项前瞻性研究,最初不仅测量医患面谈的各个方面,还测量一系列人口统计学、心理、社会和医学因素,然后记录后续的就诊行为。研究纳入了1992年6月至1995年5月间转诊的所有209例新诊断出的睾丸癌患者,184名男性同意并完成了问卷调查。不依从终点(未就诊者)为尽管收到书面提醒,但仍有两次门诊预约未就诊,且两次未就诊时间间隔至少为1个月。

结果

32名参与者(17%)被归类为未就诊者。在大多数可能预测不遵循医嘱的心理社会和医学变量方面,就诊者和未就诊者之间未发现显著差异。未就诊与患者认为与临床医生的情感关系不令人满意之间存在高度显著的关联(P = .005;风险比,3.1;95%可信区间,1.4至6.6)。

结论

那些认为与临床医生的情感关系不令人满意,包括无法信任临床医生以及感觉自己没有被当作“一个人”来对待的患者,随后更有可能无视关于后续治疗的医嘱。考虑到年轻男性可能不一定遵循男性自我依赖的刻板印象,关注他们希望与临床医生沟通的方式很重要。

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