Schmitt K, Schäfer A
Osterr Z Onkol. 1977;3(5-6):122-6.
Heterologous tumors of the uterus are commonly designated as Müllerian mixed tumors. Their origin is attributed to dispersed embryogenic isles of Müllerian duct. The always high age of the afflicted woman plus the localization in post-climacteric polyps, speak against this assumption. Five personal observations have motivated the more intensive occupation with the histiogenesis of these cases. This has led to the conclusion that these mixed tissue formations do not come from dispersed cell isles, but that the multipotency of proliferated cells has only appeared in later age in connection with a metaplasia.
子宫的异源性肿瘤通常被称为苗勒管混合瘤。其起源归因于苗勒管的散在胚胎生发岛。但患病女性的高龄以及肿瘤位于绝经后息肉中的情况,与这一假设相悖。本人的5例观察病例促使对这些病例的组织发生进行更深入研究。由此得出的结论是,这些混合性组织形成并非源自散在的细胞岛,而是增殖细胞的多能性仅在后期与化生相关联时才出现。