金氏金氏杆菌：儿童胸骨的骨关节感染：6例报告
Kingella kingae: osteoarticular infections of the sternum in children: a report of six cases.
作者信息
Luegmair Matthias, Chaker Mourad, Ploton Christine, Berard Jérôme
机构信息
Department of Orthopaedic Surgery, University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria,
出版信息
J Child Orthop. 2008 Dec;2(6):443-7. doi: 10.1007/s11832-008-0144-7. Epub 2008 Nov 18.
PURPOSE
Kingella kingae is increasingly recognized as a pathogen of osteoarticular infections (OAI) below the age of 2 years. It was reported that bones and joints which are rarely infected by other pathogens were frequently invaded by K. kingae. Based on a series of six cases, we present the typical clinical and paraclinical manifestation of K. kingae infections of the sternum and sterno-manubrial joint.
METHODS
A review of the clinical, laboratory, radiological, microbiological, and molecular data of six consecutive children admitted to a paediatric unit for OAI of the sternum was done.
RESULTS
Culture alone allowed for the detection of K. kingae as the responsible pathogen in three cases, molecular methods in the three other cases. Clinical and laboratory findings, as well as imaging methods, proved to be useful in the diagnostic process.
CONCLUSION
Our findings suggest that infections of the lower sternum and the junction between the manubrium and the xyphoid process are typical, if not pathognomonic, for the organism. A respective diagnostic and therapeutic protocol was established.
目的
金氏金杆菌日益被认为是2岁以下儿童骨关节炎感染（OAI）的病原体。据报道，很少被其他病原体感染的骨骼和关节经常被金氏金杆菌侵袭。基于一系列6例病例，我们展示了金氏金杆菌感染胸骨和胸锁关节的典型临床和辅助临床表现。
方法
对连续6名因胸骨OAI入住儿科病房的儿童的临床、实验室、放射学、微生物学和分子数据进行了回顾。
结果
仅培养法在3例中检测到金氏金杆菌为致病病原体，另外3例采用分子方法检测到。临床和实验室检查结果以及影像学方法在诊断过程中被证明是有用的。
结论
我们的研究结果表明，胸骨下部以及胸骨柄与剑突之间的连接处感染对于该病原体而言即使不是具有确诊意义，也是典型的。因此制定了相应的诊断和治疗方案。
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