DNA在手性表面的选择性吸附：超螺旋或松弛构象。
Selective adsorption of DNA on chiral surfaces: supercoiled or relaxed conformation.
作者信息
Gan Hui, Tang Kangjian, Sun Taolei, Hirtz Michael, Li Yong, Chi Lifeng, Butz Stefan, Fuchs Harald
机构信息
Physikalisches Institut, WWU Münster, Wilhelm-Klemm-Strasse 10, 48149 Müster, Germany.
出版信息
Angew Chem Int Ed Engl. 2009;48(29):5282-6. doi: 10.1002/anie.200806295.
PMID:19308941
Abstract
The right fit: Plasmid DNA molecules show chirality-dependent interaction with gold surfaces modified by L and D N-isobutyrylcysteine. Relaxed DNA molecules have a stronger interaction and adsorption on the L surface, while their counterparts on the D surface maintain a supercoiled conformation, indicating a weak interaction (see picture).
摘要
合适的匹配
质粒DNA分子与由L型和D型N - 异丁酰半胱氨酸修饰的金表面表现出依赖手性的相互作用。松弛的DNA分子在L型表面上具有更强的相互作用和吸附，而它们在D型表面上的对应物保持超螺旋构象，表明相互作用较弱（见图）。
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