Karnabatidis Dimitris, Katsanos Konstantinos, Siablis Dimitris
Department of Interventional Radiology, Patras University Hospital, Rion, Greece.
J Endovasc Ther. 2009 Feb;16 Suppl 1:I153-62. doi: 10.1583/08-2593.1.
Minimally invasive infrapopliteal angioplasty procedures are becoming the gold standard for treatment of below-the-knee arterial disease. To date, sirolimus-eluting stents have shown significant promise in inhibiting restenosis of the infrapopliteal arteries and thereby reducing recurrent leg ischemia and repeat revascularization procedures. Longer self-expanding bare stents are available to better suit the diffuse nature of atherosclerosis usually associated with critical limb ischemia. Bioabsorbable stents for transient vessel scaffolding are an elegant endovascular concept, but positive data below the knee are still lacking. It remains to be answered whether bare or drug-eluting, balloon-expandable or self-expanding, or metal versus bioabsorbable stents will have a positive impact on limb salvage to support their primary use in below-the-knee endovascular treatment.
微创腘下血管成形术正成为治疗膝下动脉疾病的金标准。迄今为止,西罗莫司洗脱支架在抑制腘下动脉再狭窄方面已显示出巨大潜力,从而减少复发性腿部缺血和重复血管重建手术。更长的自膨胀裸支架可更好地适应通常与严重肢体缺血相关的动脉粥样硬化的弥漫性。用于临时血管支架的生物可吸收支架是一个精妙的血管内概念,但膝下的阳性数据仍然缺乏。裸支架或药物洗脱支架、球囊扩张式或自膨胀式支架,以及金属支架与生物可吸收支架,是否会对肢体挽救产生积极影响以支持它们在膝下血管内治疗中的主要应用,仍有待解答。