Suppr超能文献

[卵巢浆液性“交界性”肿瘤的诊断难点]

[Diagnostic difficulties in serous "borderline" tumors of the ovary].

作者信息

Vereczkey Ildikó, Tóth Erika, Orosz Zsolt

机构信息

Országos Onkológiai Intézet Sebészi és Molekuláris Daganatpatológiai Centrum 1122 Budapest Ráth György u. 7-9, Hungary.

出版信息

Magy Onkol. 2009 Mar;53(1):23-31. doi: 10.1556/MOnkol.53.2009.1.4.

Abstract

About 15-20% of all ovarian neoplasms are of borderline type (or atypical proliferative or carcinoma of low malignant potential). They represent a common diagnostic and treatment problem both for the pathologist and for clinicians. The borderline tumors occur most commonly in childbearing age, show an indolent course and have good prognosis but are resistant to the traditional chemotherapies. The serous borderline tumors are the most common types of borderline ovarian tumors and they can cause differential diagnostic problems even for the experienced pathologist. We studied 30 cases which were diagnosed in our institute from 2000 to 2008. Thirteen were typical serous borderline tumors, in 7 cases the pattern was micropapillary, in 2 cases with microinvasion and in the remaining 8 cases the borderline tumors were associated with low-grade serous carcinomas. Seventeen of the 22 borderline cases were stage I tumors. There were noninvasive implants in the remaining 5 cases and in the cases of the low-grade carcinomas we could find, besides the noninvasive implants (in 3 cases), invasive implants or metastasis too. The main diagnostic problems in serous ovarian borderline tumors are the presence of micropapillary pattern, to detect microinvasion, or to differentiate the pseudo-borderline pattern of the low-grade serous tumors from a real borderline tumor and especially to diagnose the extraovarian diseases (types of implants). We discuss these diagnostic problems and criteria according to recent literature and our experience.

摘要

所有卵巢肿瘤中约15%-20%为交界性肿瘤(或非典型增生性肿瘤或低恶性潜能癌)。它们对病理学家和临床医生来说都是常见的诊断和治疗难题。交界性肿瘤最常发生于育龄期,病程进展缓慢,预后良好,但对传统化疗有耐药性。浆液性交界性肿瘤是最常见的交界性卵巢肿瘤类型,即使对于经验丰富的病理学家来说,它们也可能导致鉴别诊断问题。我们研究了2000年至2008年在我院诊断的30例病例。其中13例为典型浆液性交界性肿瘤,7例为微乳头型,2例有微浸润,其余8例交界性肿瘤伴有低级别浆液性癌。22例交界性病例中有17例为Ⅰ期肿瘤。其余5例有非侵袭性种植,在低级别癌病例中,除了非侵袭性种植(3例)外,我们还发现了侵袭性种植或转移。浆液性卵巢交界性肿瘤的主要诊断问题包括微乳头型的存在、微浸润的检测、将低级别浆液性肿瘤的假交界性模式与真正的交界性肿瘤区分开来,尤其是诊断卵巢外疾病(种植类型)。我们根据近期文献和我们的经验讨论这些诊断问题和标准。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验