Christian C N, Nelson P G, Peacock J, Nirenberg M
Science. 1977 May 27;196(4293):995-8. doi: 10.1126/science.193191.
Clonal neuroblastoma x glioma hybrid cells frequently formed synapses with clonal mouse striated muscle cells. Clonal myotubes were similar to cultured mouse embryo myotubes with respect to acetylcholine sensitivity and other membrane properties examined. However, acetylcholine sensitivity measurements indicate that acetylcholine receptors of clonal myotubes are distributed more uniformly over the cell surface than the receptors of cultured mouse embryo myotubes.
克隆性神经母细胞瘤与神经胶质瘤杂交细胞常与克隆性小鼠横纹肌细胞形成突触。克隆性肌管在乙酰胆碱敏感性及所检测的其他膜特性方面与培养的小鼠胚胎肌管相似。然而,乙酰胆碱敏感性测量表明,克隆性肌管的乙酰胆碱受体在细胞表面的分布比培养的小鼠胚胎肌管的受体更为均匀。