Zhao Yu-Ming, Gu Peiming, Zhang Hai-Jun, Zhang Qing-Wei, Fan Chun-An, Tu Yong-Qiang, Zhang Fu-Min
State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou 730000, PR China.
J Org Chem. 2009 Apr 17;74(8):3211-3. doi: 10.1021/jo900113s.
A short and efficient approach to aza-quaternary pyrrolo[1,2-a]azepine 8 and aza-quaternary indolizine 23, as the crucial intermediates for syntheses of stemonamine (1a) and cephalotaxine (1b), has been developed on the basis of the key intramolecular Schmidt reaction of symmetric azido-diones 5 and 18, respectively.
基于对称叠氮二酮5和18分别进行的关键分子内施密特反应，已开发出一种简短而有效的方法来合成氮杂季铵化吡咯并[1,2 - a]氮杂卓8和氮杂季铵化中氮茚23，它们是合成百部碱（1a）和三尖杉碱（1b）的关键中间体。
