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Is early onset breast cancer with no family history a good criterion for testing BRCA1 and BRCA2 genes? A small population-based study.

作者信息

Beristain E, Martínez-Bouzas C, Mallabiabarrena G, Tejada M I

出版信息

Clin Genet. 2009 Jun;75(6):576-8. doi: 10.1111/j.1399-0004.2008.01137.x. Epub 2009 Mar 23.

DOI:10.1111/j.1399-0004.2008.01137.x
PMID:19320659
Abstract
摘要

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Is early onset breast cancer with no family history a good criterion for testing BRCA1 and BRCA2 genes? A small population-based study.无家族病史的早发性乳腺癌是检测BRCA1和BRCA2基因的良好标准吗?一项基于人群的小型研究。
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引用本文的文献

1
Founder BRCA1/2 mutations in the Europe: implications for hereditary breast-ovarian cancer prevention and control.欧洲发现 BRCA1/2 基因突变:对遗传性乳腺癌-卵巢癌预防和控制的影响。
EPMA J. 2010 Sep;1(3):397-412. doi: 10.1007/s13167-010-0037-y. Epub 2010 Jun 27.
2
Breast and ovarian cancer risk evaluation in families with a disease-causing mutation in BRCA1/2.对携带BRCA1/2致病突变的家族进行乳腺癌和卵巢癌风险评估。
J Community Genet. 2010 Jun;1(2):91-9. doi: 10.1007/s12687-010-0014-0. Epub 2010 Aug 9.
3
LOH analysis should not be used as a tool to assess whether UVs of BRCA1/2 are pathogenic or not.
杂合性缺失分析不应被用作评估BRCA1/2的变异是否致病的工具。
Fam Cancer. 2010 Sep;9(3):289-90. doi: 10.1007/s10689-009-9318-9.