Brunskill S J, Hyde C J, Stanworth S J, Dorée C J, Roberts D J, Murphy M F
NHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK.
Transfus Med. 2009 Apr;19(2):59-65. doi: 10.1111/j.1365-3148.2009.00910.x. Epub 2009 Mar 23.
Clarifying the existing evidence base is crucial to improve the effectiveness of transfusion practice. The UK Systematic Review Initiative has been pursuing this objective primarily through writing systematic reviews on important topics in transfusion medicine. Here, we describe our progress for the past 5 years. We are the only research group that identifies transfusion medicine randomized controlled trials (RCTs) for the Cochrane Central Register of Controlled Trials, and to date, we have contributed 3002 RCT citations. The article considers future challenges including the need for wider involvement from the transfusion medicine community in the process of maintaining and updating systematic reviews and the identification and prioritization of topics for further clinical research including clinical trials. Collaboration between international and local research groups is important if these challenges are to be met.
明确现有证据基础对于提高输血实践的有效性至关重要。英国系统评价倡议主要通过撰写关于输血医学重要主题的系统评价来实现这一目标。在此，我们描述过去5年的进展。我们是唯一为Cochrane对照试验中央登记册识别输血医学随机对照试验（RCT）的研究小组，迄今为止，我们已贡献了3002条RCT引文。本文考虑了未来的挑战，包括输血医学界需要更广泛地参与系统评价的维护和更新过程，以及确定进一步临床研究（包括临床试验）的主题并确定其优先级。如果要应对这些挑战，国际和本地研究小组之间的合作很重要。
