Butensky James Ellen, Harmatz Paul, Lee Marion, Kennedy Christine, Petru Ann, Wara Diane, Miaskowski Christine
Department of Gastroenterology and Nutrition, Children's Hospital & Research Center Oakland, 747 52nd Street, Oakland, CA 94609, USA.
Pediatr Hematol Oncol. 2009 Mar;26(2):69-84. doi: 10.1080/08880010902754826.
Despite the high prevalence of altered iron metabolism in children with human immunodeficiency virus (HIV) disease, these alterations have not been well studied.
Twenty-six children with HIV disease underwent laboratory evaluation to determine the presence of anemia, and to classify the anemia as iron-deficiency anemia or anemia of chronic disease.
Half of the children had an alteration in iron metabolism: 6 were iron deficient, 4 had hyperferritinemia, and 3 demonstrated hyperferritinemia with iron deficiency.
These data indicate that alterations in iron metabolism are common even in the HAART era and warrant further study to identify individuals at risk for these alterations.
尽管人类免疫缺陷病毒（HIV）疾病患儿铁代谢改变的患病率很高，但这些改变尚未得到充分研究。
26名HIV疾病患儿接受了实验室评估，以确定是否存在贫血，并将贫血分类为缺铁性贫血或慢性病贫血。
一半的患儿存在铁代谢改变：6名缺铁，4名铁蛋白血症，3名表现为伴有缺铁的铁蛋白血症。
这些数据表明，即使在高效抗逆转录病毒治疗（HAART）时代，铁代谢改变也很常见，需要进一步研究以确定有这些改变风险的个体。
