Ladurner Ruth, Feilitzsch Maximilian, Steurer Wolfgang, Coerper Stephan, Königsrainer Alfred, Beckert Stefan
Department of General, Visceral and Transplant Surgery, University Hospital Tübingen, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany.
Microvasc Res. 2009 May;77(3):387-8. doi: 10.1016/j.mvr.2009.01.008. Epub 2009 Feb 7.
The intraoperative measurement of the peripheral microperfusion after liver transplantation is connected with quite an effort and a continuous evaluation in the postoperative follow up is not possible till now.
Before mobilization of the liver during surgical intervention the following parameters were measured on the surface of the right (segment 7/8) and the left (segment 2/3) liver lobe with a probe, combining laser-Doppler-flowmetry and tissue-spectrometry: the oxygen saturation (SO2), the relative capillary hemoglobin concentration (rHB), the blood flow (flow) and the blood flow velocity (velo). In addition the peripheral oxygen saturation (SPO2), the central venous pressure (ZVP), the positive endexspiratory pressure (PEEP) and the hemoglobin (HB) were documented.
9 patients (median age 75 years) were included in the study. SPO2, ZVP, PEEP and HB were regular. The parameters SO2, rHB, flow and velo showed no significant changes between the right and the left liver lobe.
The O2C-method allows a reproducible intraoperative evaluation of the hepatic microcirculation.
肝移植术中对周围微灌注的测量颇费周折，且迄今为止术后随访期间无法进行持续评估。
在手术干预过程中肝脏游离前，使用结合激光多普勒血流仪和组织光谱仪的探头，在右肝叶（第7/8段）和左肝叶（第2/3段）表面测量以下参数：氧饱和度（SO2）、相对毛细血管血红蛋白浓度（rHB）、血流量（flow）和血流速度（velo）。此外，记录外周血氧饱和度（SPO2）、中心静脉压（ZVP）、呼气末正压（PEEP）和血红蛋白（HB）。
9名患者（中位年龄75岁）纳入研究。SPO2、ZVP、PEEP和HB均正常。SO2、rHB、flow和velo参数在右肝叶和左肝叶之间无显著变化。
O2C方法可对肝脏微循环进行可重复的术中评估。
