Nakasuji-Yamate 3-6-24, Takarazuka, 665-0875, Japan.
Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.
Int J Mol Sci. 2008 Sep;9(9):1595-1620. doi: 10.3390/ijms9091595. Epub 2008 Sep 1.
Most bacteria that swim are propelled by flagellar filaments, which are driven by a rotary motor powered by proton flux. The mechanism of the flagellar motor is discussed by reforming the model proposed by the present authors in 2005. It is shown that the mean strength of Coulomb field produced by a proton passing the channel is very strong in the Mot assembly so that the Mot assembly can be a shear force generator and induce the flagellar rotation. The model gives clear calculation results in agreement with experimental observations, e g., for the characteristic torque-velocity relationship of the flagellar rotation.
大多数游动的细菌都是由鞭毛丝推动的,而鞭毛丝的运动则由质子流驱动的旋转电机提供动力。本文通过对 2005 年提出的模型进行改进,对鞭毛马达的工作机制进行了讨论。结果表明,在马达组件中,质子通过通道产生的库仑场的平均强度非常大,因此马达组件可以作为一个剪切力发生器,并诱导鞭毛旋转。该模型给出了与实验观察结果一致的清晰计算结果,例如,对于鞭毛旋转的特征转矩-速度关系。