Stämpfli Martin R, Anderson Gary P
Department of Pathology and Molecular Medicine, Centre for Gene Therapeutics, McMaster University, Hamilton, Ontario, Canada.
Nat Rev Immunol. 2009 May;9(5):377-84. doi: 10.1038/nri2530.
A complex and multilayered immune defence system protects the host against harmful agents and maintains tissue homeostasis. Cigarette smoke exposure markedly impacts the immune system, compromising the host's ability to mount appropriate immune and inflammatory responses and contributing to smoking-related pathologies. These adverse effects on the immune system not only occur in active smokers, but also in those exposed to smoke passively in contaminated environments, and may persist for decades after exposure has ended.
一个复杂且多层的免疫防御系统保护宿主抵御有害因子并维持组织稳态。接触香烟烟雾会显著影响免疫系统，损害宿主产生适当免疫和炎症反应的能力，并导致与吸烟相关的病理状况。这些对免疫系统的不利影响不仅发生在主动吸烟者中，也发生在那些在受污染环境中被动接触烟雾的人身上，并且可能在接触结束后持续数十年。
