Faculty of Health and Environmental Sciences, Auckland University of Technology, Private Bag 92006, Auckland 1142, New Zealand.
Br J Nutr. 2009 Sep;102(5):786-91. doi: 10.1017/S0007114509274794. Epub 2009 Mar 31.
We sought to identify the sex-specific cut-off in waist circumference which best identifies those with metabolic abnormalities consistent with the metabolic syndrome (MS) among Maori, the indigenous people of New Zealand of Polynesian origin. In 3816 self-identified Maori (2742 women, 1344 men) a 75 g oral glucose tolerance test, fasting lipid, anthropometric and blood pressure measurements were made. MS components were defined by Adult Treatment Panel (ATP) III criteria. Waist cut-off was defined using receiver operating characteristic (ROC) curve analysis to define the presence of at least two of the other MS components ( > or = 2MS). Prevalence of > or = 2MS was high (42.1 %). In males and females, waist was as good, or better, a predictor of > or = 2MS (area under ROC 0.73 women, 0.68 men) as waist:hip ratio (0.66, 0.67), BMI (0.72, 0.68) or percentage body fat (0.70, 0.68). The prediction of dysglycaemia using anthropometric variables followed a similar pattern to > or = 2MS. Waist circumference to predict > or = 2MS or dysglycaemia in Maori women and men was 98 cm and 103 cm. Applying this cut-off to the International Diabetes Federation (IDF) criteria would identify 27.8 % (34.0 % males, 25.5 % females) with the MS with an OR for > or = 2MS (adjusted for sex, smoking and age) of 3.5 (95 % CI 3.1, 4.0). Age >48 years, smoking and being male increased the odds of the MS. These waist cut-offs should be considered in both clinical practice and to optimise the definition of the MS for Maori. The validity of these criteria in other Polynesian groups should be confirmed.
我们旨在确定腰围的性别特异性切点，以便在新西兰毛利人群中识别出代谢异常与代谢综合征（MS）一致的人群。在 3816 名自认为是毛利人的个体中（2742 名女性，1344 名男性），进行了 75 克口服葡萄糖耐量试验、空腹血脂、人体测量学和血压测量。MS 成分根据成人治疗小组 (ATP) III 标准定义。腰围切点使用接收者操作特征 (ROC) 曲线分析来定义存在至少两个其他 MS 成分（≥2MS）。≥2MS 的患病率很高（42.1%）。在男性和女性中，腰围与腰围与臀围比（0.66，0.67）、BMI（0.72，0.68）或体脂百分比（0.70，0.68）一样，或更好地预测≥2MS（ROC 下面积 0.73 女性，0.68 男性）。使用人体测量学变量预测糖代谢异常遵循与≥2MS 相似的模式。腰围预测毛利女性和男性的≥2MS 或糖代谢异常的切点为 98cm 和 103cm。将此切点应用于国际糖尿病联合会 (IDF) 标准将识别出 27.8%（34.0%男性，25.5%女性）患有 MS，其≥2MS 的 OR（调整性别、吸烟和年龄后）为 3.5（95%CI 3.1，4.0）。年龄>48 岁、吸烟和男性增加了 MS 的几率。在临床实践和优化 MS 对毛利人的定义时应考虑这些腰围切点。应在其他波利尼西亚人群中确认这些标准的有效性。
