Craig A D, Hunsley S J
Division of Neurobiology, Barrow Neurological Institute, Phoenix, AZ 85013.
Brain Res. 1991 Aug 30;558(1):93-7. doi: 10.1016/0006-8993(91)90719-c.
The possibility that morphine might differentially affect spinal neurons responsive to small-diameter thermoreceptive-specific afferents was tested. Systemic morphine enhanced a portion or all of the stimulus-response function of 7 of 9 lamina I spinothalamic tract cells specifically sensitive to cold applied to the glabrous hindpaw in the cat. This result contrasts strongly with the predominant inhibition of nociceptive lamina I neurons by morphine.
对吗啡是否可能差异性地影响对小直径热感受特异性传入纤维有反应的脊髓神经元进行了测试。全身性吗啡增强了猫后爪无毛区冷刺激时，9个脊髓背角I层脊髓丘脑束细胞中7个细胞的部分或全部刺激-反应功能，这些细胞对冷刺激特别敏感。这一结果与吗啡对伤害性I层神经元的主要抑制作用形成了强烈对比。
