Naidech Andrew M, Bernstein Richard A, Levasseur Kimberly, Bassin Sarice L, Bendok Bernard R, Batjer H Hunt, Bleck Thomas P, Alberts Mark J
Department of Neurology, Northwestern University, Chicago, IL 60611, USA.
Ann Neurol. 2009 Mar;65(3):352-6. doi: 10.1002/ana.21618.
There are few data on platelet function in intracerebral hemorrhage (ICH). We prospectively enrolled 69 patients with ICH and measured platelet function on admission. Aspirin use before ICH was associated with reduced platelet activity. Less platelet activity was associated with intraventricular hemorrhage (516.5 [interquartile range (IQR), 454-629.25] vs 637 [IQR, 493-654] aspirin reaction units; p = 0.04) and death at 14 days (480.5 [IQR, 444.5-632.5] vs 626 [IQR, 494-652] aspirin reaction units; p = 0.04). Objective measures of platelet function on admission are associated with intraventricular hemorrhage and death after ICH.
关于脑出血（ICH）患者血小板功能的数据较少。我们前瞻性地纳入了69例脑出血患者，并在入院时测量了血小板功能。脑出血前使用阿司匹林与血小板活性降低有关。血小板活性较低与脑室内出血（阿司匹林反应单位：516.5[四分位间距（IQR），454 - 629.25] vs 637[IQR，493 - 654]；p = 0.04）和14天内死亡（阿司匹林反应单位：480.5[IQR，444.5 - 632.5] vs 626[IQR，494 - 652]；p = 0.04）相关。入院时血小板功能的客观指标与脑出血后的脑室内出血和死亡有关。
