Siltovuori A, Tirri R, Harri M N
Acta Physiol Scand. 1977 Apr;99(4):457-61. doi: 10.1111/j.1748-1716.1977.tb10398.x.
Decreased chronotropic and inotropic sensitivity of isolated atria to phenylephrine but not to isoprenaline was found in rats following repeated physical training by swimming or repeated ACTH-injections. These changes were induced within a week of subjection of animals to these treatments. It is concluded, that these effects are mediated by increased adrenergic activity which results in this subsensitivity of alpha-receptors.
在大鼠中，通过游泳进行反复体能训练或反复注射促肾上腺皮质激素后，发现离体心房对去氧肾上腺素的变时性和变力性敏感性降低，但对异丙肾上腺素的敏感性未降低。这些变化在动物接受这些处理后的一周内诱发。得出的结论是，这些效应是由肾上腺素能活性增加介导的，这导致了α受体的这种敏感性降低。
