Riopelle R J, Dow K E, Verge V M, Richardson P M
Department of Medicine, Queen's University, Kingston, Ontario, Canada.
Can J Neurol Sci. 1991 Aug;18(3 Suppl):398-402. doi: 10.1017/s0317167100032534.
The extracellular environment of the neuron provides a heterogeneous milieu of survival and growth modulating molecular species subserving regulatory signals that operate in development, mediate activity-dependent enduring changes in synaptic connectivity, and promote or inhibit survival and axonal regeneration following insult. Parallel distributed processing networks in neurons, activated by these molecular species, can likely be recruited selectively to serve specific needs of the organism.
神经元的细胞外环境提供了一个由生存和生长调节分子种类构成的异质环境，这些分子种类支持在发育过程中起作用、介导突触连接中依赖活动的持久变化，并在受到损伤后促进或抑制生存和轴突再生的调节信号。由这些分子种类激活的神经元中的并行分布式处理网络，可能能够被选择性地招募来满足生物体的特定需求。
