Lunghetti Stefano, Zacà Valerio, Maffei Silvia, Carrera Arcangelo, Gaddi Rosaria, Diciolla Francesco, Maccherini Massimo, Chiavarelli Mario, Mondillo Sergio, Favilli Roberto
Acute Card Care. 2009;11(4):250-1. doi: 10.1080/17482940902842564.
Abuse of doping agents may pose a higher risk for heart disease including acute myocardial infarction. We report the case of a 50-year-old body-builder Caucasian man with a long-standing abuse of nandrolone and erythropoietin that developed a ventricular septal defect following acute myocardial infarction. This mechanical complication led to cardiogenic shock ultimately treated with the implantation of a circulatory support by means of extracorporeal membrane oxygenation. The patient subsequently underwent orthotopic heart transplantation. The association of intense isometric exercise, abuse of erythropoietin and nandrolone is likely to have predisposed to coronary thrombus formation and acute myocardial infarction, as the patient presented no traditional cardiovascular risk factors.
滥用兴奋剂可能会增加患心脏病的风险，包括急性心肌梗死。我们报告了一例50岁的白人健美运动员，长期滥用诺龙和促红细胞生成素，在急性心肌梗死后出现室间隔缺损。这种机械性并发症导致心源性休克，最终通过体外膜肺氧合植入循环支持装置进行治疗。患者随后接受了原位心脏移植。由于该患者没有传统的心血管危险因素，剧烈的等长运动、滥用促红细胞生成素和诺龙之间的关联可能易导致冠状动脉血栓形成和急性心肌梗死。
