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Early detection (9+6 weeks) of cardiac failure in a fetus diagnosed as Turner syndrome by 2D transvaginal ultrasound-guided coelocentesis.

作者信息

Tonni Gabriele, Azzoni Daniela, Ventura Alessandro, De Felice Claudio, Marinelli Maria

机构信息

Division of Obstetrics and Gynecology, Guastalla Provincial Hospital, AUSL Reggio Emilia, Reggio Emilia, Italy.

出版信息

J Clin Ultrasound. 2009 Jun;37(5):302-4. doi: 10.1002/jcu.20575.

DOI:10.1002/jcu.20575
PMID:19337987
Abstract

A 28-year-old woman was diagnosed by transvaginal ultrasound at 9+6 weeks with early fetal cardiac failure (hydrothorax and bradycardia). Doppler analysis of ductus venosus showed a negative A-wave pattern. The follow-up sonogram obtained at 11+6 weeks documented a missed abortion. A transvaginal ultrasound-guided coelocentesis was performed under local cervical anesthesia before uterine suction and 8 mL of clear extracoelomic fluid were successfully aspirated. Cytogenetic analysis demonstrated a 45,X karyotype. Ultrasound and Doppler waveform analysis of ductus venosus allowed early diagnosis of fetal cardiac failure. Coelocentesis may be the method of choice for early fetal karyotyping and may be used in the future to induce immunologic tolerance.

摘要

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