Kowalczyk J R, Dmoszyńska A, Chobotow M, Sokolowska B
Institute of Pediatrics, Medical Academy, Lublin, Poland.
Cancer Genet Cytogenet. 1991 Sep;55(2):173-9. doi: 10.1016/0165-4608(91)90075-6.
Fourteen patients diagnosed as having multiple myeloma were studied cytogenetically. In eight patients a sufficient number of metaphases was obtained and four of them showed abnormal karyotypes of bone marrow cells. Hypodiploidy was a consistent finding, as was the involvement of chromosome 9.
对14例诊断为多发性骨髓瘤的患者进行了细胞遗传学研究。在8例患者中获得了足够数量的中期分裂相，其中4例显示骨髓细胞染色体核型异常。亚二倍体是一个一致的发现，9号染色体受累也是如此。
