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米托蒽醌心脏毒性评估中的心室晚电位

Ventricular late potentials in the assessment of mitoxantrone cardiotoxicity.

作者信息

de Leonardis V, Bartalucci S, Cinelli P, De Scalzi M, Becucci A, Lottini G, Neri B

机构信息

Istituto di Clinica Medica Generale e Terapia Medica IV, Università degli Studi, Firenze, Italia.

出版信息

Cardiology. 1991;79(2):110-5. doi: 10.1159/000174867.

Abstract

Sixteen female patients underwent signal-averaged electrocardiography and radionuclide angiography for the assessment of the resting left ventricular ejection fraction in the course of chemotherapy with mitoxantrone (MTX) for advanced breast cancer. Nine patients had received prior cardiotoxic treatments. Our findings indicate that patients treated with MTX may develop late potentials.

摘要

16名女性患者在接受米托蒽醌(MTX)化疗晚期乳腺癌的过程中,接受了信号平均心电图和放射性核素血管造影检查,以评估静息状态下的左心室射血分数。9名患者之前接受过心脏毒性治疗。我们的研究结果表明,接受MTX治疗的患者可能会出现晚电位。

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