缓激肽2型受体基因的插入/缺失多态性影响舒张压。
Insertion/deletion polymorphism of the bradykinin type 2 receptor gene influence diastolic blood pressure.
作者信息
Freitas S R, Pereira A C, Floriano M S, Mill J G, Krieger J E
出版信息
J Hum Hypertens. 2009 Aug;23(8):553-5. doi: 10.1038/jhh.2009.23. Epub 2009 Apr 2.
PMID:19339996
Abstract
The contribution of kinins to the beneficial effects in cardiovascular risk reductions remains unclear. In this context, the present study examined whether the +9 bp/-9 bp polymorphism in bradykinin type 2 receptor gene, predicts hypertension risk in a large urban Brazilian population. Our finding indicated that the -9 bp allele may contribute to hypertension because of increased diastolic pressure.
摘要
激肽在降低心血管风险方面的有益作用仍不明确。在此背景下，本研究调查了缓激肽2型受体基因中+9 bp/-9 bp多态性是否可预测巴西一个大型城市人群的高血压风险。我们的研究结果表明，-9 bp等位基因可能由于舒张压升高而导致高血压。
Zotero 插件