Ives C L, Akoh J A, George J, Vaughan-Huxley E, Lawson H
Directorate of Surgery and Renal Services, Plymouth Hospitals NHS Trust, Derriford Hospital, Plymouth, UK.
J Vasc Access. 2009 Jan-Mar;10(1):37-42. doi: 10.1177/112972980901000107.
To increase the proportion of dialysis patients using native arteriovenous fistulae (AVF), improved selection of the most appropriate procedure must be coupled with early access surveillance to determine which access would likely mature and when intervention might lead to access salvage. This study was aimed at auditing pre-operative vessel mapping and post-operative access surveillance against the primary outcome measure of AVF maturation.
Between January 2006 and August 2007, 113 AVF created in 101 patients were studied. Data on pre-operative vessel mapping, type of AVF, post-operative surveillance scans were analyzed against the outcome AVF.
Pre-operative mapping and post-operative scanning were carried out in 86% and 91%, respectively. A maturing fistula on post-operative scan highly correlated with a satisfactory outcome (p<0.001). The sensitivity and specificity of the post-operative scan were 100% and 85%, respectively. There were 79 brachiocephalic and 34 radiocephalic fistulae with a primary failure rate of 23% and 47%, respectively, giving an overall failure rate of 30%. Nine fistulae had further intervention (angioplasty or thrombolysis) and five (56%) were salvaged. Seventy-two AVF matured satisfactorily giving a primary cumulative patency of 71% (72/102).
This study shows that preoperative vessel mapping provides useful information regarding the choice of AVF. Access surveillance duplex scanning at 6-8 weeks post-operatively is viable and has a high sensitivity and specificity for final outcome of fistula. Identifying AVF with potential problems early means that further intervention or surgery can be planned earlier, which will have a positive impact on patients.
为提高使用自体动静脉内瘘(AVF)的透析患者比例,必须改进最合适手术方式的选择,并结合早期通路监测,以确定哪种通路可能成熟以及何时进行干预可能挽救通路。本研究旨在对照AVF成熟这一主要结局指标,审核术前血管造影和术后通路监测情况。
对2006年1月至2007年8月期间101例患者所创建的113个AVF进行研究。针对结局AVF,分析术前血管造影、AVF类型、术后监测扫描的数据。
分别有86%和91%的患者进行了术前造影和术后扫描。术后扫描显示成熟的内瘘与满意结局高度相关(p<0.001)。术后扫描的敏感性和特异性分别为100%和85%。有79个肱头型和34个桡头型内瘘,原发性失败率分别为23%和47%,总体失败率为30%。9个内瘘接受了进一步干预(血管成形术或溶栓),其中5个(56%)得以挽救。72个AVF成熟情况良好,原发性累积通畅率为71%(72/102)。
本研究表明,术前血管造影可为AVF的选择提供有用信息。术后6 - 8周进行通路监测双功扫描是可行的,对瘘管最终结局具有高敏感性和特异性。早期识别有潜在问题的AVF意味着可以更早地规划进一步干预或手术,这将对患者产生积极影响。