用乙烷二甲磺酸盐损害睾丸间质细胞功能后雄性大鼠的促性腺激素水平。
Gonadotrophin levels in male rats following impairment of Leydig cell function by ethylene dimethanesulphonate.
作者信息
Jackson C M, Morris I D
出版信息
Andrologia. 1977 Jan-Mar;9(1):29-35. doi: 10.1111/j.1439-0272.1977.tb01255.x.
Abstract
The effects of the antispermatogenic compound, ethylene dimethanesulphonate on anterior pituitary and serum FSH, LH and prolactin levels in male rats were investigated. A rapid and sustained rise in serum LH, reaching castrate levels, indictated a normal pituitary response to androgen deprivation. Whilst no change in prolactin was observed, serum FSH showed a biphasic increase which is discussed in relation to the spermatogenic process.
摘要
研究了抗生精化合物甲磺酸乙二酯对雄性大鼠垂体前叶以及血清促卵泡激素（FSH）、促黄体生成素（LH）和催乳素水平的影响。血清LH迅速且持续升高，达到去势水平，表明垂体对雄激素剥夺有正常反应。虽然未观察到催乳素变化，但血清FSH呈现双相增加，这与生精过程相关并进行了讨论。
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