Ziessman Harvey A
Division of Nuclear Medicine, Russell H. Morgan Department of Radiology and Radiologic Science, Johns Hopkins Medical Institutions, Baltimore, MD 21278-0817, USA.
Semin Nucl Med. 2009 May;39(3):174-85. doi: 10.1053/j.semnuclmed.2008.12.002.
Since the early 1980s interventions have been used in conjunction with (99m)Tc-iminodiacetic acid (IDA) radiopharmaceuticals in many different clinical situations, eg, to prepare the patient for the study, to reduce the time of a study, to improve its diagnostic accuracy, and to make diagnoses not otherwise possible. Interventions all have underlying physiological rationales. Some of these interventions are as simple as having the patient fast before the study or eat a meal with high fat content. However, most are pharmacologic interventions, eg, morphine sulfate, cholecystokinin, and phenobarbital. Although these are probably the most common interventions used today, numerous other interventions have been used during the years and likely will be in the future. Interventions have aided in the diagnosis of acute cholecystitis, chronic cholecystitis, biliary obstruction, and sphincter of Oddi dysfunction. This review will discuss in detail the interventions commonly is use today and in somewhat less detail many that have been successfully used on an investigational basis and may have some larger role in the future.
自20世纪80年代初以来，在许多不同的临床情况下，干预措施已与（99m）锝亚氨基二乙酸（IDA）放射性药物联合使用，例如，为患者进行检查做准备、缩短检查时间、提高诊断准确性以及做出其他情况下无法做出的诊断。所有干预措施都有其潜在的生理原理。其中一些干预措施很简单，比如让患者在检查前禁食或食用高脂肪含量的食物。然而，大多数是药物干预，例如硫酸吗啡、胆囊收缩素和苯巴比妥。尽管这些可能是目前最常用的干预措施，但多年来还使用了许多其他干预措施，而且未来可能还会继续使用。干预措施有助于诊断急性胆囊炎、慢性胆囊炎、胆道梗阻和Oddi括约肌功能障碍。本综述将详细讨论目前常用的干预措施，并较少详细地讨论许多已在研究基础上成功使用且未来可能发挥更大作用的干预措施。
