Mostaza Jose M, Martín-Jadraque Raquel, Vicente Ignacio, San Martin Miguel A, Lahoz Carlos
Atherosclerosis Unit, Hospital Carlos III, Madrid, Spain.
Cerebrovasc Dis. 2009;27 Suppl 1:77-81. doi: 10.1159/000200443. Epub 2009 Apr 3.
Cerebrovascular disease is one of the leading causes of morbidity and mortality in developed countries. The identification of at-risk individuals is a high priority so that efficacious preventive measures can be implemented. Subjects with the highest risk of cerebrovascular diseases are those who already have had a stroke or a transient ischemic attack, and those with vascular disease in other territories, either in coronary or peripheral arteries. Other subjects at risk are those with cardiac disease, such as atrial fibrillation, those with hypertension, diabetes and smoking habit, as well as individuals with subclinical vascular disease. Although there is considerable evidence for the efficacy of preventive treatment in this population, the percentage of patients receiving optimum treatment is far from ideal. There is a need to implement strategies in the population directed towards increasing awareness of the need to establish healthy habits and adequate preventive pharmacological treatment that could reduce the incidence of this debilitating disease.
脑血管疾病是发达国家发病和死亡的主要原因之一。识别高危个体是当务之急,以便能够实施有效的预防措施。脑血管疾病风险最高的人群是那些已经发生过中风或短暂性脑缺血发作的人,以及在其他部位患有血管疾病的人,无论是冠状动脉还是外周动脉。其他高危人群包括患有心脏病(如心房颤动)的人、高血压患者、糖尿病患者和有吸烟习惯的人,以及患有亚临床血管疾病的个体。尽管有大量证据表明预防性治疗对这一人群有效,但接受最佳治疗的患者比例仍远不理想。有必要在人群中实施相关策略,以提高人们对养成健康习惯和进行适当预防性药物治疗必要性的认识,从而降低这种使人衰弱疾病的发病率。