银屑病的病理生理学
Pathophysiology of psoriasis.
作者信息
Voorhees J J
出版信息
Annu Rev Med. 1977;28:467-73. doi: 10.1146/annurev.me.28.020177.002343.
Abstract
Psoriasis is a disease characterized by benign but unrestricted epithelial growth. The molecular pathophysiology of this unregulated growth has been discussed. A better understanding of the role of the cell surface, cyclic nucleotides, arachidonic acid-prostaglandin metabolism, and polyamines in psoriasis may clarify our understanding of this disease and produce clues pertinent to a general understanding of growth regulation.
摘要
银屑病是一种以良性但不受限制的上皮细胞生长为特征的疾病。这种不受调控的生长的分子病理生理学已被讨论。更好地理解细胞表面、环核苷酸、花生四烯酸 - 前列腺素代谢和多胺在银屑病中的作用，可能会阐明我们对这种疾病的理解，并产生与生长调控的一般理解相关的线索。
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