Newman Diane K
PENN Center for Continence and Pelvic Health, Division of Urology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA.
Director. 2008 Winter;16(1):22-5.
This article provides an overview of the results of the MATRIX study. Subsequent articles will provide more detailed results of other findings in this study. Overall, this study found that OXY-TDS administration resulted in improvement in HRQoL, with the medication having its greatest effect on the impact of incontinence, severity of symptoms, and role limitations. OXY-TDS was well tolerated, with a low prevalence of anticholinergic adverse events noted. The next article will focus on results in populations older than 65 years and in those older than 80 years.
本文概述了MATRIX研究的结果。后续文章将提供该研究其他发现的更详细结果。总体而言,本研究发现使用OXY-TDS可改善健康相关生活质量,该药物对尿失禁影响、症状严重程度及角色限制的作用最为显著。OXY-TDS耐受性良好,抗胆碱能不良事件的发生率较低。下一篇文章将聚焦于65岁以上人群及80岁以上人群的研究结果。