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头颈部细胞系创建以及用于研究和药物开发的组织采集的伦理与技术考量(第二部分):获取组织标本的伦理方面

Ethical and technical considerations for the creation of cell lines in the head & neck and tissue harvesting for research and drug development (Part II): ethical aspects of obtaining tissue specimens.

作者信息

Upile Tahwinder, Jerjes Waseem, Kafas Panagiotis, Singh Sandeep U, Mahil Jaspal, Sandison Ann, Hopper Colin, Sudhoff Holger

机构信息

Head & Neck Centre, University College London Hospital, London, UK.

出版信息

Int Arch Med. 2009 Apr 3;2(1):9. doi: 10.1186/1755-7682-2-9.

Abstract

BACKGROUND

Although much has been published for the development of cell lines, these were lab based and developed for scientific technical staff.

OBJECTIVE OF REVIEW

We discuss the ethical implications of tissue retention and present a generic consent form (Part II). We also present a simple and successful protocol for the development of cell lines and tissue harvesting for the clinical scientist (Part I).

CONCLUSION

Consent is also more proximate and assurance can be given of appropriate usage. Ethical questions concerning tissue ownership are in many institutions raised during the current consenting procedure. We provide a robust ethical framework, based on the current legislation, which allows clinicians to be directly involved in cell and tissue harvesting.

摘要

背景

尽管关于细胞系的开发已经发表了很多内容,但这些都是基于实验室的,是为科研技术人员开发的。

综述目的

我们讨论组织留存的伦理问题,并提供一份通用的同意书(第二部分)。我们还为临床科学家提供了一个简单且成功的细胞系开发和组织采集方案(第一部分)。

结论

同意也更为直接,并且可以保证适当使用。在当前的同意程序中,许多机构都提出了关于组织所有权的伦理问题。我们基于现行立法提供了一个强有力的伦理框架,使临床医生能够直接参与细胞和组织的采集。

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